2ECL

Solution Structure of the RING domain of the human RING-box protein 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	CYS18
A	CYS21
A	HIS53
A	CYS56

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	CYS29
A	CYS32
A	CYS41
A	CYS55

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 601

Chain	Residue
A	HIS50
A	CYS67
A	CYS70
A	CYS48

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	42
Details	ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175

Chain	Residue	Details
A	CYS29-GLN71

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:34518685, ECO:0007744|PDB:7ONI

Chain	Residue	Details
A	CYS18
A	CYS56
A	CYS67
A	CYS70
A	CYS21
A	CYS29
A	CYS32
A	CYS41
A	CYS48
A	HIS50
A	HIS53
A	CYS55

---