2ECI

Solution structure of the RING domain of the human TNF receptor-associated factor 6 protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0016567	biological_process	protein ubiquitination

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	CYS28
A	ILE30
A	CYS31
A	ARG36

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	CYS43
A	GLY44
A	HIS45

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Functional Information from PROSITE/UniProt

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CgHrFCkaCI

Chain	Residue	Details
A	CYS43-ILE52

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	39
Details	ZN_FING: RING-type => ECO:0000255|PROSITE-ProRule:PRU00175

Chain	Residue	Details
A	CYS28-ASN67

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site_id	SWS_FT_FI2
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:17135271, ECO:0000269|PubMed:19825828

Chain	Residue	Details
A	LYS82

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