2EBT

Solution structure of three tandem repeats of zf-C2H2 domains from human Kruppel-like factor 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003700	molecular_function	DNA-binding transcription factor activity
A	0006355	biological_process	regulation of transcription, DNA-templated

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 100

Chain	Residue
A	CYS375
A	CYS380
A	HIS393
A	HIS397

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 200

Chain	Residue
A	CYS405
A	CYS410
A	HIS423
A	HIS427

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 300

Chain	Residue
A	CYS438
A	HIS451
A	HIS455
A	CYS435

---

Functional Information from PROSITE/UniProt

site_id	PS00028
Number of Residues	23
Details	ZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CdypgCtkvYtksshlkaHlrt..H

Chain	Residue	Details
A	CYS375-HIS397
A	CYS405-HIS427
A	CYS435-HIS455

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Zinc finger: {"description":"C2H2-type 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	24
Details	Zinc finger: {"description":"C2H2-type 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	22
Details	Zinc finger: {"description":"C2H2-type 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00042","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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