2E9Z

Foot-and-mouth disease virus RNA-polymerase in complex with a template- primer RNA, ATP and UTP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0003968	molecular_function	RNA-directed RNA polymerase activity
A	0006351	biological_process	DNA-templated transcription
A	0039694	biological_process	viral RNA genome replication

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG A 1030

Chain	Residue
A	ASP238
A	ASP339
A	THR384

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG A 1031

Chain	Residue
A	TYR241
A	UTP993

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site_id	AC3
Number of Residues	13
Details	BINDING SITE FOR RESIDUE UTP A 993

Chain	Residue
A	VAL181
A	SER242
A	ASP245
A	SER298
A	ASP338
A	PPV665
A	MG1031
B	A903
C	A921
A	LYS164
A	ARG168
A	ARG179
A	ILE180

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site_id	AC4
Number of Residues	9
Details	BINDING SITE FOR RESIDUE PPV A 665

Chain	Residue
A	GLU166
A	ARG179
A	LYS387
A	UTP993
A	HOH1036
A	HOH1046
C	HOH527
C	C920
C	A921

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