2E8W
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and IPP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004161 | molecular_function | dimethylallyltranstransferase activity |
A | 0004311 | molecular_function | farnesyltranstransferase activity |
A | 0004337 | molecular_function | geranyltranstransferase activity |
A | 0004659 | molecular_function | prenyltransferase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0005739 | cellular_component | mitochondrion |
A | 0008299 | biological_process | isoprenoid biosynthetic process |
A | 0015031 | biological_process | protein transport |
A | 0016114 | biological_process | terpenoid biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0033384 | biological_process | geranyl diphosphate biosynthetic process |
A | 0033386 | biological_process | geranylgeranyl diphosphate biosynthetic process |
A | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0004161 | molecular_function | dimethylallyltranstransferase activity |
B | 0004311 | molecular_function | farnesyltranstransferase activity |
B | 0004337 | molecular_function | geranyltranstransferase activity |
B | 0004659 | molecular_function | prenyltransferase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0005739 | cellular_component | mitochondrion |
B | 0008299 | biological_process | isoprenoid biosynthetic process |
B | 0015031 | biological_process | protein transport |
B | 0016114 | biological_process | terpenoid biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0033384 | biological_process | geranyl diphosphate biosynthetic process |
B | 0033386 | biological_process | geranylgeranyl diphosphate biosynthetic process |
B | 0045337 | biological_process | farnesyl diphosphate biosynthetic process |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 1201 |
Chain | Residue |
A | ASP80 |
A | ASP84 |
A | HOH539 |
A | HOH540 |
A | IPE1001 |
A | MG1202 |
site_id | AC2 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE MG A 1202 |
Chain | Residue |
A | HOH677 |
A | IPE1001 |
A | MG1201 |
A | ASP80 |
A | ASP84 |
A | HOH538 |
site_id | AC3 |
Number of Residues | 4 |
Details | BINDING SITE FOR RESIDUE MG B 1203 |
Chain | Residue |
B | ASP80 |
B | ASP84 |
B | IPE1002 |
B | MG1204 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE MG B 1204 |
Chain | Residue |
B | ASP80 |
B | ASP84 |
B | HOH401 |
B | IPE1002 |
B | MG1203 |
site_id | AC5 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE IPE A 1001 |
Chain | Residue |
A | ASP80 |
A | ASP84 |
A | ARG89 |
A | LEU143 |
A | LYS174 |
A | GLN211 |
A | ASP214 |
A | LYS238 |
A | HOH459 |
A | HOH539 |
A | HOH540 |
A | HOH589 |
A | HOH677 |
A | MG1201 |
A | MG1202 |
site_id | AC6 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE IPE B 1002 |
Chain | Residue |
B | SER76 |
B | ASP80 |
B | ASP84 |
B | ARG89 |
B | LEU143 |
B | LYS174 |
B | GLN211 |
B | ASP214 |
B | LYS238 |
B | HOH526 |
B | HOH785 |
B | IPE1003 |
B | MG1203 |
B | MG1204 |
site_id | AC7 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE IPE B 1003 |
Chain | Residue |
B | LYS38 |
B | PRO39 |
B | GLY40 |
B | ARG44 |
B | HIS73 |
B | LEU77 |
B | ARG90 |
B | TYR210 |
B | GLN211 |
B | ASP214 |
B | HOH631 |
B | HOH796 |
B | IPE1002 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 20 |
Details | BINDING: BINDING => ECO:0000269|PubMed:17535895 |
Chain | Residue | Details |
A | LYS41 | |
A | LYS238 | |
B | LYS41 | |
B | ARG44 | |
B | HIS73 | |
B | ARG89 | |
B | ARG90 | |
B | LYS174 | |
B | THR175 | |
B | GLN211 | |
B | ASN218 | |
A | ARG44 | |
B | LYS238 | |
A | HIS73 | |
A | ARG89 | |
A | ARG90 | |
A | LYS174 | |
A | THR175 | |
A | GLN211 | |
A | ASN218 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000269|PubMed:16554305, ECO:0000269|PubMed:17535895 |
Chain | Residue | Details |
A | ASP80 | |
A | ASP84 | |
B | ASP80 | |
B | ASP84 |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: BINDING => ECO:0000305|PubMed:17535895 |
Chain | Residue | Details |
A | LYS228 | |
B | LYS228 |
site_id | SWS_FT_FI4 |
Number of Residues | 2 |
Details | SITE: Important for determining product chain length |
Chain | Residue | Details |
A | TYR112 | |
B | TYR112 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1fps |
Chain | Residue | Details |
A | TYR210 | |
A | ARG89 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1fps |
Chain | Residue | Details |
B | TYR210 | |
B | ARG89 |