2E55

Structure of AQ2163 protein from Aquifex aeolicus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
A	0004845	molecular_function	uracil phosphoribosyltransferase activity
A	0005525	molecular_function	GTP binding
A	0005829	cellular_component	cytosol
A	0006178	biological_process	guanine salvage
A	0006223	biological_process	uracil salvage
A	0008655	biological_process	pyrimidine-containing compound salvage
A	0016757	molecular_function	glycosyltransferase activity
A	0032263	biological_process	GMP salvage
A	0032264	biological_process	IMP salvage
A	0044206	biological_process	UMP salvage
A	0046100	biological_process	hypoxanthine metabolic process
B	0000287	molecular_function	magnesium ion binding
B	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
B	0004845	molecular_function	uracil phosphoribosyltransferase activity
B	0005525	molecular_function	GTP binding
B	0005829	cellular_component	cytosol
B	0006178	biological_process	guanine salvage
B	0006223	biological_process	uracil salvage
B	0008655	biological_process	pyrimidine-containing compound salvage
B	0016757	molecular_function	glycosyltransferase activity
B	0032263	biological_process	GMP salvage
B	0032264	biological_process	IMP salvage
B	0044206	biological_process	UMP salvage
B	0046100	biological_process	hypoxanthine metabolic process
C	0000287	molecular_function	magnesium ion binding
C	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
C	0004845	molecular_function	uracil phosphoribosyltransferase activity
C	0005525	molecular_function	GTP binding
C	0005829	cellular_component	cytosol
C	0006178	biological_process	guanine salvage
C	0006223	biological_process	uracil salvage
C	0008655	biological_process	pyrimidine-containing compound salvage
C	0016757	molecular_function	glycosyltransferase activity
C	0032263	biological_process	GMP salvage
C	0032264	biological_process	IMP salvage
C	0044206	biological_process	UMP salvage
C	0046100	biological_process	hypoxanthine metabolic process
D	0000287	molecular_function	magnesium ion binding
D	0004422	molecular_function	hypoxanthine phosphoribosyltransferase activity
D	0004845	molecular_function	uracil phosphoribosyltransferase activity
D	0005525	molecular_function	GTP binding
D	0005829	cellular_component	cytosol
D	0006178	biological_process	guanine salvage
D	0006223	biological_process	uracil salvage
D	0008655	biological_process	pyrimidine-containing compound salvage
D	0016757	molecular_function	glycosyltransferase activity
D	0032263	biological_process	GMP salvage
D	0032264	biological_process	IMP salvage
D	0044206	biological_process	UMP salvage
D	0046100	biological_process	hypoxanthine metabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 1301

Chain	Residue
A	ARG102
A	ALA132
A	THR133
A	GLY134
A	GLY135
A	THR136
A	HOH1314

---

site_id	AC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 1302

Chain	Residue
B	ALA132
B	THR133
B	GLY134
B	GLY135
B	THR136
B	HOH1395
B	ARG102
B	SER109

---

site_id	AC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE SO4 C 1303

Chain	Residue
C	ARG102
C	ALA132
C	THR133
C	GLY134
C	GLY135
C	THR136
C	HOH1315
C	HOH1377
C	HOH1398

---

site_id	AC4
Number of Residues	10
Details	BINDING SITE FOR RESIDUE SO4 D 1304

Chain	Residue
D	ARG102
D	ALA132
D	THR133
D	GLY134
D	GLY135
D	THR136
D	HOH1328
D	HOH1329
D	HOH1376
D	HOH1385

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01218

Chain	Residue	Details
A	ARG77
B	ILE191
B	GLY196
B	ASP197
C	ARG77
C	ARG102
C	ASP128
C	ILE191
C	GLY196
C	ASP197
D	ARG77
A	ARG102
D	ARG102
D	ASP128
D	ILE191
D	GLY196
D	ASP197
A	ASP128
A	ILE191
A	GLY196
A	ASP197
B	ARG77
B	ARG102
B	ASP128

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
A	ARG102
A	THR106
A	ASP197

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
B	ARG102
B	THR106
B	ASP197

---

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
C	ARG102
C	THR106
C	ASP197

---

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1bd3

Chain	Residue	Details
D	ARG102
D	THR106
D	ASP197

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