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2E4X

Crystal structure of the extracellular region of the group II metabotropic glutamate receptor complexed with 1S,3R-ACPD

Functional Information from GO Data
ChainGOidnamespacecontents
A0004930molecular_functionG protein-coupled receptor activity
A0007186biological_processG protein-coupled receptor signaling pathway
A0016020cellular_componentmembrane
B0004930molecular_functionG protein-coupled receptor activity
B0007186biological_processG protein-coupled receptor signaling pathway
B0016020cellular_componentmembrane
Functional Information from PROSITE/UniProt
site_idPS00979
Number of Residues19
DetailsG_PROTEIN_RECEP_F3_1 G-protein coupled receptors family 3 signature 1. VaNLLrLFqIPQISyASTS
ChainResidueDetails
AVAL157-SER175

site_idPS00980
Number of Residues23
DetailsG_PROTEIN_RECEP_F3_2 G-protein coupled receptors family 3 signature 2. CCWiCipCepyeYlv...DefTCmdC
ChainResidueDetails
ACYS527-CYS549

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues12
DetailsBINDING:
ChainResidueDetails
AARG68
BTYR222
BASP301
BLYS389
ASER151
AALA172
ATYR222
AASP301
ALYS389
BARG68
BSER151
BALA172

site_idSWS_FT_FI2
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17360426
ChainResidueDetails
AASN209
BASN209

site_idSWS_FT_FI3
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN292
AGLN414
BASN292
BGLN414

site_idSWS_FT_FI4
Number of Residues2
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0007744|PubMed:24090084
ChainResidueDetails
AGLN439
BGLN439

218853

PDB entries from 2024-04-24

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