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2E3N

Crystal structure of CERT START domain in complex with C6-ceramide (P212121)

Functional Information from GO Data
ChainGOidnamespacecontents
A0008289molecular_functionlipid binding
Functional Information from PDB Data
site_idAC1
Number of Residues11
DetailsBINDING SITE FOR RESIDUE 6CM A 600
ChainResidue
APHE436
AGLU575
AHOH618
AARG442
AGLU446
AGLN467
AHIS469
AVAL480
ATYR482
AASN504
ATYR553

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:18184806, ECO:0000269|PubMed:20036255
ChainResidueDetails
AVAL472
ATHR493
AGLN530
APHE579

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0007744|PubMed:23186163
ChainResidueDetails
AGLU372

site_idSWS_FT_FI3
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
AGLU373
ATHR380

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648
ChainResidueDetails
AASN377

225946

PDB entries from 2024-10-09

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