2E2S
Solution structure of agelenin, an insecticidal peptide from the venom of Agelena opulenta
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005246 | molecular_function | calcium channel regulator activity |
| A | 0005576 | cellular_component | extracellular region |
| A | 0035821 | biological_process | modulation of process of another organism |
| A | 0044231 | cellular_component | host cell presynaptic membrane |
| A | 0090729 | molecular_function | toxin activity |
| A | 0099106 | molecular_function | ion channel regulator activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NH2 A 36 |
| Chain | Residue |
| A | HIS6 |
| A | LYS23 |
| A | LEU35 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 34 |
| Details | Peptide: {"description":"U2-agatoxin-Aop1a","featureId":"PRO_0000044985"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Site: {"description":"Critical for insecticidal activity","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Leucine amide","evidences":[{"source":"PubMed","id":"1421801","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17644092","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"1991","firstPage":"357","lastPage":"363","volume":"12","journal":"Biomed. Res.","title":"Agelenin, a spider neurotoxin: determination of the C-terminus as amide form, and investigation of the disulfide bond arrangement.","authors":["Hagiwara K.","Inui T.","Nakajima K.","Kimura T.","Kitada C.","Fujino M.","Sakakibara S.","Nakajima T."]}}]} |
| Chain | Residue | Details |
