2E1Y

Crystal structure of propionate kinase (TdcD) from Salmonella typhimurium

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006082	biological_process	organic acid metabolic process
A	0006083	biological_process	acetate metabolic process
A	0008776	molecular_function	acetate kinase activity
A	0008980	molecular_function	propionate kinase activity
A	0016301	molecular_function	kinase activity
A	0016310	biological_process	phosphorylation
A	0016774	molecular_function	phosphotransferase activity, carboxyl group as acceptor
A	0046872	molecular_function	metal ion binding
A	0070689	biological_process	L-threonine catabolic process to propionate

Functional Information from PROSITE/UniProt

site_id	PS01075
Number of Residues	12
Details	ACETATE_KINASE_1 Acetate and butyrate kinases family signature 1. VLvINcGSSSiK

Chain	Residue	Details
A	VAL7-LYS18

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site_id	PS01076
Number of Residues	18
Details	ACETATE_KINASE_2 Acetate and butyrate kinases family signature 2. LIvaHlGnGaSIcAvrnG

Chain	Residue	Details
A	LEU199-GLY216

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_01881

Chain	Residue	Details
A	ASP143

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01881

Chain	Residue	Details
A	LYS18
A	ARG86
A	GLY326
A	GLU381
A	ASN11

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site_id	SWS_FT_FI3
Number of Residues	3
Details	BINDING:

Chain	Residue	Details
A	HIS203
A	ASP278
A	HIS175

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site_id	SWS_FT_FI4
Number of Residues	2
Details	SITE: Transition state stabilizer => ECO:0000255|HAMAP-Rule:MF_01881

Chain	Residue	Details
A	HIS175
A	ARG236

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