Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004522 | molecular_function | ribonuclease A activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| A | 0050830 | biological_process | defense response to Gram-positive bacterium |
| A | 0051607 | biological_process | defense response to virus |
| A | 0070062 | cellular_component | extracellular exosome |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004518 | molecular_function | nuclease activity |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004522 | molecular_function | ribonuclease A activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
| B | 0050830 | biological_process | defense response to Gram-positive bacterium |
| B | 0051607 | biological_process | defense response to virus |
| B | 0070062 | cellular_component | extracellular exosome |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1001 |
| Chain | Residue |
| A | GLU125 |
| A | GLU125 |
| B | GLU125 |
| B | GLU125 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1002 |
| Chain | Residue |
| A | CL2001 |
| A | CL2001 |
| A | CL2002 |
| A | CL2002 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD A 1004 |
| Chain | Residue |
| A | CL2005 |
| A | CL2006 |
| A | HOH2111 |
| A | ASP126 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CD A 1006 |
| Chain | Residue |
| A | HIS119 |
| A | CL2009 |
| A | HOH2153 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD A 1008 |
| Chain | Residue |
| A | GLU49 |
| A | HIS80 |
| A | CL2011 |
| A | HOH2033 |
| A | HOH2122 |
| A | HOH2132 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 2001 |
| Chain | Residue |
| A | LYS102 |
| A | ARG104 |
| A | SER123 |
| A | CD1002 |
| A | CD1002 |
| A | CL2002 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL A 2002 |
| Chain | Residue |
| A | LYS102 |
| A | ARG104 |
| A | ARG104 |
| A | GLU125 |
| A | CD1002 |
| A | CD1002 |
| A | CL2001 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 2005 |
| Chain | Residue |
| A | ASP83 |
| A | ARG85 |
| A | SER100 |
| A | LYS102 |
| A | ASP126 |
| A | CD1004 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 2006 |
| Chain | Residue |
| A | LYS74 |
| A | ARG85 |
| A | VAL124 |
| A | CD1004 |
| site_id | BC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL A 2009 |
| Chain | Residue |
| A | HIS12 |
| A | HIS119 |
| A | PHE120 |
| A | CD1006 |
| A | HOH2063 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL A 2011 |
| Chain | Residue |
| A | GLU49 |
| A | HIS80 |
| A | CD1008 |
| A | HOH2019 |
| A | HOH2096 |
| B | SER77 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 1003 |
| Chain | Residue |
| B | CL2003 |
| B | CL2003 |
| B | CL2004 |
| B | CL2004 |
| site_id | BC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CD B 1005 |
| Chain | Residue |
| B | GLU49 |
| B | HIS80 |
| B | CL2007 |
| B | CL2008 |
| B | HOH2093 |
| B | HOH2122 |
| site_id | BC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CD B 1007 |
| Chain | Residue |
| B | HIS119 |
| B | CL2010 |
| B | HOH2187 |
| B | HOH2205 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CL B 2003 |
| Chain | Residue |
| B | LYS102 |
| B | ARG104 |
| B | SER123 |
| B | CD1003 |
| B | CD1003 |
| B | CL2004 |
| site_id | BC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL B 2004 |
| Chain | Residue |
| B | LYS102 |
| B | ARG104 |
| B | ARG104 |
| B | GLU125 |
| B | CD1003 |
| B | CD1003 |
| B | CL2003 |
| site_id | BC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CL B 2007 |
| Chain | Residue |
| A | SER77 |
| B | GLU49 |
| B | HIS80 |
| B | CD1005 |
| B | CL2008 |
| B | HOH2021 |
| B | HOH2097 |
| site_id | BC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 2008 |
| Chain | Residue |
| A | SER77 |
| B | HIS80 |
| B | CD1005 |
| B | CL2007 |
| B | HOH2093 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CL B 2010 |
| Chain | Residue |
| B | HIS12 |
| B | HIS119 |
| B | PHE120 |
| B | CD1007 |
| B | HOH2052 |
Functional Information from PROSITE/UniProt
| site_id | PS00127 |
| Number of Residues | 7 |
| Details | RNASE_PANCREATIC Pancreatic ribonuclease family signature. CKpvNTF |
| Chain | Residue | Details |
| A | CYS40-PHE46 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 40 |
| Details | Region: {"description":"Disordered","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Compositional bias: {"description":"Basic and acidic residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; partial","evidences":[{"source":"PubMed","id":"3202829","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"3202829","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rbn |
| Chain | Residue | Details |
| A | PHE120 | |
| A | HIS119 | |
| A | HIS12 | |
| A | LYS41 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rbn |
| Chain | Residue | Details |
| B | PHE120 | |
| B | HIS119 | |
| B | HIS12 | |
| B | LYS41 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1rbn |
| Chain | Residue | Details |
| A | HIS119 | |
| A | HIS12 | |
| A | LYS41 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1rbn |
| Chain | Residue | Details |
| B | HIS119 | |
| B | HIS12 | |
| B | LYS41 | |
