2DZB
Crystal Structure of Dihydropteroate Synthase from Thermus thermophilus HB8 in complex with 6HMPPP
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004156 | molecular_function | dihydropteroate synthase activity |
A | 0005829 | cellular_component | cytosol |
A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
A | 0016740 | molecular_function | transferase activity |
A | 0042558 | biological_process | pteridine-containing compound metabolic process |
A | 0044237 | biological_process | cellular metabolic process |
A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
A | 0046656 | biological_process | folic acid biosynthetic process |
A | 0046872 | molecular_function | metal ion binding |
B | 0004156 | molecular_function | dihydropteroate synthase activity |
B | 0005829 | cellular_component | cytosol |
B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
B | 0016740 | molecular_function | transferase activity |
B | 0042558 | biological_process | pteridine-containing compound metabolic process |
B | 0044237 | biological_process | cellular metabolic process |
B | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
B | 0046656 | biological_process | folic acid biosynthetic process |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | BINDING SITE FOR RESIDUE HH2 A 1301 |
Chain | Residue |
A | VAL34 |
A | LYS233 |
A | ARG268 |
A | HIS270 |
A | HOH1309 |
A | HOH1351 |
A | HOH1358 |
A | ASN36 |
A | ASP109 |
A | ASN128 |
A | MET152 |
A | ASP197 |
A | PHE202 |
A | LEU227 |
A | GLY229 |
site_id | AC2 |
Number of Residues | 17 |
Details | BINDING SITE FOR RESIDUE HH2 B 1302 |
Chain | Residue |
B | VAL34 |
B | ASN36 |
B | THR76 |
B | ASP109 |
B | ASN128 |
B | VAL150 |
B | MET152 |
B | ASP197 |
B | PHE202 |
B | LEU227 |
B | GLY229 |
B | LYS233 |
B | ARG268 |
B | HIS270 |
B | HOH1304 |
B | HOH1331 |
B | HOH1451 |
Functional Information from PROSITE/UniProt
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1aj0 |
Chain | Residue | Details |
A | ARG268 | |
A | ASN36 |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1aj0 |
Chain | Residue | Details |
B | ARG268 | |
B | ASN36 |