2DZB
Crystal Structure of Dihydropteroate Synthase from Thermus thermophilus HB8 in complex with 6HMPPP
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004156 | molecular_function | dihydropteroate synthase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0042558 | biological_process | pteridine-containing compound metabolic process |
| A | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| A | 0046656 | biological_process | folic acid biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004156 | molecular_function | dihydropteroate synthase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0009396 | biological_process | folic acid-containing compound biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0042558 | biological_process | pteridine-containing compound metabolic process |
| B | 0046654 | biological_process | tetrahydrofolate biosynthetic process |
| B | 0046656 | biological_process | folic acid biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE HH2 A 1301 |
| Chain | Residue |
| A | VAL34 |
| A | LYS233 |
| A | ARG268 |
| A | HIS270 |
| A | HOH1309 |
| A | HOH1351 |
| A | HOH1358 |
| A | ASN36 |
| A | ASP109 |
| A | ASN128 |
| A | MET152 |
| A | ASP197 |
| A | PHE202 |
| A | LEU227 |
| A | GLY229 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HH2 B 1302 |
| Chain | Residue |
| B | VAL34 |
| B | ASN36 |
| B | THR76 |
| B | ASP109 |
| B | ASN128 |
| B | VAL150 |
| B | MET152 |
| B | ASP197 |
| B | PHE202 |
| B | LEU227 |
| B | GLY229 |
| B | LYS233 |
| B | ARG268 |
| B | HIS270 |
| B | HOH1304 |
| B | HOH1331 |
| B | HOH1451 |
Functional Information from PROSITE/UniProt
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1aj0 |
| Chain | Residue | Details |
| A | ARG268 | |
| A | ASN36 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1aj0 |
| Chain | Residue | Details |
| B | ARG268 | |
| B | ASN36 |
