Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000049 | molecular_function | tRNA binding |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004818 | molecular_function | glutamate-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006424 | biological_process | glutamyl-tRNA aminoacylation |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016874 | molecular_function | ligase activity |
| A | 0043039 | biological_process | tRNA aminoacylation |
| B | 0000049 | molecular_function | tRNA binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004818 | molecular_function | glutamate-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006424 | biological_process | glutamyl-tRNA aminoacylation |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016874 | molecular_function | ligase activity |
| B | 0043039 | biological_process | tRNA aminoacylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG D 902 |
| Chain | Residue |
| D | HOH1139 |
| D | HOH1302 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE ATP B 602 |
| Chain | Residue |
| B | ARG47 |
| B | ALA206 |
| B | GLU208 |
| B | TRP209 |
| B | LEU235 |
| B | LEU236 |
| B | ILE244 |
| B | GAU702 |
| B | HOH1235 |
| B | HOH1268 |
| D | A576 |
| B | SER9 |
| B | THR11 |
| B | HIS15 |
| B | GLY17 |
| B | THR18 |
| B | TYR20 |
| B | ILE21 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE ATP A 601 |
| Chain | Residue |
| A | PRO8 |
| A | SER9 |
| A | THR11 |
| A | HIS15 |
| A | GLY17 |
| A | THR18 |
| A | ILE21 |
| A | ARG47 |
| A | ALA206 |
| A | GLU208 |
| A | TRP209 |
| A | LEU235 |
| A | LEU236 |
| A | ILE244 |
| A | GAU701 |
| A | HOH1040 |
| C | A576 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GAU A 701 |
| Chain | Residue |
| A | ARG5 |
| A | ALA7 |
| A | GLU41 |
| A | TYR187 |
| A | ASN191 |
| A | ARG205 |
| A | TRP209 |
| A | ATP601 |
| C | A576 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE GAU B 702 |
| Chain | Residue |
| B | ARG5 |
| B | ALA7 |
| B | SER9 |
| B | GLU41 |
| B | TYR187 |
| B | ASN191 |
| B | ARG205 |
| B | TRP209 |
| B | ATP602 |
| B | HOH1268 |
| D | A576 |
Functional Information from PROSITE/UniProt
| site_id | PS00178 |
| Number of Residues | 12 |
| Details | AA_TRNA_LIGASE_I Aminoacyl-transfer RNA synthetases class-I signature. PspTGdPHVGTA |
| Chain | Residue | Details |
| A | PRO8-ALA19 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 30 |
| Details | Region: {"description":"Interaction with tRNA"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | Motif: {"description":"'HIGH' region","evidences":[{"source":"HAMAP-Rule","id":"MF_00022","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Motif: {"description":"'KMSKS' region","evidences":[{"source":"HAMAP-Rule","id":"MF_00022","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 30 |
| Details | Binding site: {} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00022","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Interaction with tRNA; via carbonyl oxygen"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | Site: {"description":"Essential for discrimination between tRNA(Glu) and tRNA(Gln)"} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j09 |
| Chain | Residue | Details |
| A | LYS246 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1j09 |
| Chain | Residue | Details |
| B | LYS246 | |
| site_id | MCSA1 |
| Number of Residues | 1 |
| Details | M-CSA 318 |
| site_id | MCSA2 |
| Number of Residues | 1 |
| Details | M-CSA 318 |
