2DXC
Recombinant thiocyanate hydrolase, fully-matured form
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0016787 | molecular_function | hydrolase activity |
A | 0018760 | molecular_function | thiocyanate hydrolase activity |
A | 0046265 | biological_process | thiocyanate catabolic process |
B | 0016787 | molecular_function | hydrolase activity |
B | 0018760 | molecular_function | thiocyanate hydrolase activity |
B | 0046265 | biological_process | thiocyanate catabolic process |
C | 0003824 | molecular_function | catalytic activity |
C | 0016787 | molecular_function | hydrolase activity |
C | 0018760 | molecular_function | thiocyanate hydrolase activity |
C | 0046265 | biological_process | thiocyanate catabolic process |
C | 0046872 | molecular_function | metal ion binding |
C | 0046914 | molecular_function | transition metal ion binding |
D | 0016787 | molecular_function | hydrolase activity |
D | 0018760 | molecular_function | thiocyanate hydrolase activity |
D | 0046265 | biological_process | thiocyanate catabolic process |
E | 0016787 | molecular_function | hydrolase activity |
E | 0018760 | molecular_function | thiocyanate hydrolase activity |
E | 0046265 | biological_process | thiocyanate catabolic process |
F | 0003824 | molecular_function | catalytic activity |
F | 0016787 | molecular_function | hydrolase activity |
F | 0018760 | molecular_function | thiocyanate hydrolase activity |
F | 0046265 | biological_process | thiocyanate catabolic process |
F | 0046872 | molecular_function | metal ion binding |
F | 0046914 | molecular_function | transition metal ion binding |
G | 0016787 | molecular_function | hydrolase activity |
G | 0018760 | molecular_function | thiocyanate hydrolase activity |
G | 0046265 | biological_process | thiocyanate catabolic process |
H | 0016787 | molecular_function | hydrolase activity |
H | 0018760 | molecular_function | thiocyanate hydrolase activity |
H | 0046265 | biological_process | thiocyanate catabolic process |
I | 0003824 | molecular_function | catalytic activity |
I | 0016787 | molecular_function | hydrolase activity |
I | 0018760 | molecular_function | thiocyanate hydrolase activity |
I | 0046265 | biological_process | thiocyanate catabolic process |
I | 0046872 | molecular_function | metal ion binding |
I | 0046914 | molecular_function | transition metal ion binding |
J | 0016787 | molecular_function | hydrolase activity |
J | 0018760 | molecular_function | thiocyanate hydrolase activity |
J | 0046265 | biological_process | thiocyanate catabolic process |
K | 0016787 | molecular_function | hydrolase activity |
K | 0018760 | molecular_function | thiocyanate hydrolase activity |
K | 0046265 | biological_process | thiocyanate catabolic process |
L | 0003824 | molecular_function | catalytic activity |
L | 0016787 | molecular_function | hydrolase activity |
L | 0018760 | molecular_function | thiocyanate hydrolase activity |
L | 0046265 | biological_process | thiocyanate catabolic process |
L | 0046872 | molecular_function | metal ion binding |
L | 0046914 | molecular_function | transition metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE 3CO C 301 |
Chain | Residue |
C | CYS128 |
C | CSD131 |
C | SER132 |
C | CSO133 |
C | TLA3001 |
site_id | AC2 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE 3CO F 301 |
Chain | Residue |
F | CSO133 |
E | TLA3002 |
F | CYS128 |
F | CSD131 |
F | SER132 |
site_id | AC3 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE 3CO I 301 |
Chain | Residue |
I | CYS128 |
I | CSD131 |
I | SER132 |
I | CSO133 |
I | TLA3003 |
site_id | AC4 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE 3CO L 301 |
Chain | Residue |
L | CYS128 |
L | CSD131 |
L | SER132 |
L | CSO133 |
L | TLA3004 |
site_id | AC5 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE TLA C 3001 |
Chain | Residue |
B | ARG90 |
B | ARG91 |
B | GLN94 |
B | ASN95 |
B | TYR108 |
B | TRP112 |
C | SER108 |
C | CSD131 |
C | SER132 |
C | CSO133 |
C | ARG136 |
C | 3CO301 |
C | HOH3009 |
C | HOH3020 |
site_id | AC6 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE TLA E 3002 |
Chain | Residue |
E | ARG90 |
E | ARG91 |
E | GLN94 |
E | ASN95 |
E | TYR108 |
E | TRP112 |
F | SER108 |
F | CSD131 |
F | SER132 |
F | CSO133 |
F | ARG136 |
F | 3CO301 |
F | HOH330 |
site_id | AC7 |
Number of Residues | 13 |
Details | BINDING SITE FOR RESIDUE TLA I 3003 |
Chain | Residue |
H | ARG90 |
H | ARG91 |
H | GLN94 |
H | ASN95 |
H | TYR108 |
H | TRP112 |
I | CSD131 |
I | SER132 |
I | CSO133 |
I | ARG136 |
I | 3CO301 |
I | HOH3014 |
I | HOH3034 |
site_id | AC8 |
Number of Residues | 14 |
Details | BINDING SITE FOR RESIDUE TLA L 3004 |
Chain | Residue |
K | ARG90 |
K | ARG91 |
K | GLN94 |
K | ASN95 |
K | TYR108 |
K | TRP112 |
L | SER108 |
L | CSD131 |
L | SER132 |
L | CSO133 |
L | ARG136 |
L | 3CO301 |
L | HOH3014 |
L | HOH3028 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 16 |
Details | BINDING: BINDING => ECO:0007744|PDB:2DD5 |
Chain | Residue | Details |
C | THR129 | |
I | SER132 | |
I | CSO133 | |
I | TYR134 | |
L | THR129 | |
L | SER132 | |
L | CSO133 | |
L | TYR134 | |
C | SER132 | |
C | CSO133 | |
C | TYR134 | |
F | THR129 | |
F | SER132 | |
F | CSO133 | |
F | TYR134 | |
I | THR129 |
site_id | SWS_FT_FI2 |
Number of Residues | 4 |
Details | MOD_RES: Cysteine sulfinic acid (-SO2H) => ECO:0000269|PubMed:16417356, ECO:0000269|PubMed:16879822, ECO:0000269|PubMed:17222425 |
Chain | Residue | Details |
C | SER132 | |
F | SER132 | |
I | SER132 | |
L | SER132 |
site_id | SWS_FT_FI3 |
Number of Residues | 4 |
Details | MOD_RES: Cysteine sulfenic acid (-SOH) => ECO:0000269|PubMed:16879822, ECO:0000269|PubMed:17222425 |
Chain | Residue | Details |
C | TYR134 | |
F | TYR134 | |
I | TYR134 | |
L | TYR134 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ahj |
Chain | Residue | Details |
H | ARG91 |
site_id | CSA2 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ahj |
Chain | Residue | Details |
K | ARG91 |
site_id | CSA3 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ahj |
Chain | Residue | Details |
E | ARG91 |
site_id | CSA4 |
Number of Residues | 1 |
Details | Annotated By Reference To The Literature 1ahj |
Chain | Residue | Details |
B | ARG91 |
site_id | MCSA1 |
Number of Residues | 4 |
Details | M-CSA 284 |
Chain | Residue | Details |
C | THR129 | activator, electrostatic stabiliser, metal ligand |
C | SER132 | electrostatic stabiliser, metal ligand |
C | CSO133 | electrostatic stabiliser, metal ligand |
C | TYR134 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, metal ligand |
site_id | MCSA2 |
Number of Residues | 4 |
Details | M-CSA 284 |
Chain | Residue | Details |
F | THR129 | activator, electrostatic stabiliser, metal ligand |
F | SER132 | electrostatic stabiliser, metal ligand |
F | CSO133 | electrostatic stabiliser, metal ligand |
F | TYR134 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, metal ligand |
site_id | MCSA3 |
Number of Residues | 4 |
Details | M-CSA 284 |
Chain | Residue | Details |
I | THR129 | activator, electrostatic stabiliser, metal ligand |
I | SER132 | electrostatic stabiliser, metal ligand |
I | CSO133 | electrostatic stabiliser, metal ligand |
I | TYR134 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, metal ligand |
site_id | MCSA4 |
Number of Residues | 4 |
Details | M-CSA 284 |
Chain | Residue | Details |
L | THR129 | activator, electrostatic stabiliser, metal ligand |
L | SER132 | electrostatic stabiliser, metal ligand |
L | CSO133 | electrostatic stabiliser, metal ligand |
L | TYR134 | activator, electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, metal ligand |