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2DWD

crystal structure of KcsA-FAB-TBA complex in Tl+

Functional Information from GO Data
ChainGOidnamespacecontents
C0005249molecular_functionvoltage-gated potassium channel activity
C0006813biological_processpotassium ion transport
C0008076cellular_componentvoltage-gated potassium channel complex
Functional Information from PDB Data
site_idAC1
Number of Residues12
DetailsBINDING SITE FOR RESIDUE TL C 3001
ChainResidue
CGLY77
CTL3002
CTL3002
CTL3002
CGLY77
CGLY77
CGLY77
CTYR78
CTYR78
CTYR78
CTYR78
CTL3002

site_idAC2
Number of Residues16
DetailsBINDING SITE FOR RESIDUE TL C 3002
ChainResidue
CVAL76
CVAL76
CVAL76
CVAL76
CGLY77
CGLY77
CGLY77
CGLY77
CTL3001
CTL3001
CTL3001
CTL3001
CTL3003
CTL3003
CTL3003
CTL3003

site_idAC3
Number of Residues12
DetailsBINDING SITE FOR RESIDUE TL C 3003
ChainResidue
CTHR75
CTHR75
CTHR75
CTHR75
CVAL76
CVAL76
CVAL76
CVAL76
CTL3002
CTL3002
CTL3002
CTL3002

site_idAC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE TL C 3004
ChainResidue
CTHR75
CTHR75
CTHR75
CTHR75
CTBA4001
CTBA4001
CTBA4001
CTBA4001

site_idAC5
Number of Residues7
DetailsBINDING SITE FOR RESIDUE L2C C 201
ChainResidue
BTYR50
BGLU53
CPRO63
CARG64
CTRP67
CLEU86
CARG89

site_idAC6
Number of Residues1
DetailsBINDING SITE FOR RESIDUE F09 A 220
ChainResidue
AARG57

site_idAC7
Number of Residues19
DetailsBINDING SITE FOR RESIDUE TBA C 4001
ChainResidue
CALA73
CALA73
CALA73
CALA73
CTHR74
CTHR74
CTHR74
CTHR74
CTHR75
CTHR75
CTHR75
CTHR75
CILE100
CILE100
CILE100
CTL3004
CTL3004
CTL3004
CTL3004

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
BTYR192-HIS198

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues45
DetailsTRANSMEM: Helical
ChainResidueDetails
CALA28-ALA50
CGLY88-ALA111

site_idSWS_FT_FI2
Number of Residues16
DetailsTOPO_DOM: Extracellular
ChainResidueDetails
CGLU51-THR61
CLEU81-TRP87

site_idSWS_FT_FI3
Number of Residues10
DetailsINTRAMEM: Helical; Pore-forming
ChainResidueDetails
CTYR62-THR72

site_idSWS_FT_FI4
Number of Residues7
DetailsINTRAMEM: Pore-forming
ChainResidueDetails
CALA73-ASP80

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PDB entries from 2024-10-30

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