2DVQ
Crystal structure analysis of the N-terminal bromodomain of human BRD2 complexed with acetylated histone H4 peptide
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 60 |
| Details | BROMODOMAIN_1 Bromodomain signature. AwpFrqpvDavklglpDYHkiIkqpMdmgtIkrrlenny..Ywaasecmqdfnt.MftNCyiY |
| Chain | Residue | Details |
| A | ALA96-TYR155 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:22343720 |
| Chain | Residue | Details |
| P | LYS5 | |
| C | TYR155 | |
| C | ASN156 | |
| C | LYS157 | |
| P | LYS8 | |
| P | ALY12 | |
| Q | LYS5 | |
| Q | LYS8 | |
| Q | ALY12 | |
| B | ASN156 | |
| B | LYS157 | |
| C | ASP112 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:20048151, ECO:0007744|PDB:2DVQ, ECO:0007744|PDB:2DVS |
| Chain | Residue | Details |
| A | ASP160 | |
| A | ASP161 | |
| B | ASP160 | |
| B | ASP161 | |
| C | ASP160 | |
| C | ASP161 |
