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2DQU

Crystal form II: high resolution crystal structure of the complex of the hydrolytic antibody Fab 6D9 and a transition-state analog

Replaces:  1HYY
Functional Information from GO Data
ChainGOidnamespacecontents
H0002250biological_processadaptive immune response
H0002376biological_processimmune system process
H0003823molecular_functionantigen binding
H0005576cellular_componentextracellular region
H0016064biological_processimmunoglobulin mediated immune response
H0019814cellular_componentimmunoglobulin complex
L0002250biological_processadaptive immune response
L0002376biological_processimmune system process
L0005576cellular_componentextracellular region
L0005886cellular_componentplasma membrane
L0019814cellular_componentimmunoglobulin complex
L0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues21
DetailsBINDING SITE FOR RESIDUE CPD H 501
ChainResidue
HALA33
HPHE100
HALA129
HARG213
HASP214
HHOH522
LHIS27
LPHE89
LGLY91
LSER92
LVAL94
HSER50
LGLU213
LCYS214
HSER52
HTYR58
HVAL95
HHIS97
HASP99
HGLY100
HTRP100

Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCEATH
ChainResidueDetails
LTYR192-HIS198

238268

PDB entries from 2025-07-02

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