2DOS

Structural basis for the recognition of Lys48-linked polyubiquitin chain by the Josephin domain of ataxin-3, a putative deubiquitinating enzyme

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004843	molecular_function	cysteine-type deubiquitinase activity
A	0016579	biological_process	protein deubiquitination

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"23625928","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"33157014","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"16020535","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16118278","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Active site: {"evidences":[{"source":"PubMed","id":"16020535","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"16118278","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Cross-link: {"description":"Peptide (Met-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"23696636","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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