Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002283 | biological_process | neutrophil activation involved in immune response |
| A | 0002673 | biological_process | regulation of acute inflammatory response |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003779 | molecular_function | actin binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004530 | molecular_function | deoxyribonuclease I activity |
| A | 0004536 | molecular_function | DNA nuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005634 | cellular_component | nucleus |
| A | 0005635 | cellular_component | nuclear envelope |
| A | 0006308 | biological_process | DNA catabolic process |
| A | 0006915 | biological_process | apoptotic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0031410 | cellular_component | cytoplasmic vesicle |
| A | 0042588 | cellular_component | zymogen granule |
| A | 0070948 | biological_process | regulation of neutrophil mediated cytotoxicity |
Functional Information from PDB Data
| site_id | ACT |
| Number of Residues | 5 |
| Details | |
| Chain | Residue |
| A | GLU39 |
| A | GLU78 |
| A | HIS134 |
| A | ASP212 |
| A | HIS252 |
Functional Information from PROSITE/UniProt
| site_id | PS00918 |
| Number of Residues | 8 |
| Details | DNASE_I_2 Deoxyribonuclease I signature 2. GDFNAdCS |
| Chain | Residue | Details |
| A | GLY167-SER174 | |
| site_id | PS00919 |
| Number of Residues | 21 |
| Details | DNASE_I_1 Deoxyribonuclease I signature 1. IVALHSAPsdavaEINsLyDV |
| Chain | Residue | Details |
| A | ILE130-VAL150 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"2395459","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"2395459","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"4976790","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Involved in actin-binding","evidences":[{"source":"PubMed","id":"2395459","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Site: {"description":"Nitration by tetranitromethane destroys a Ca(2+) binding site and inactivates enzyme"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"1748997","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3560229","evidenceCode":"ECO:0000269"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1dnk |
| Chain | Residue | Details |
| A | ASP212 | |
| A | HIS134 | |
| A | GLU78 | |
| A | HIS252 | |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 41 |
