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2DLL

Solution structure of the IRF domain of human interferon regulator factors 4

Functional Information from GO Data
ChainGOidnamespacecontents
A0000976molecular_functiontranscription cis-regulatory region binding
A0003700molecular_functionDNA-binding transcription factor activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PROSITE/UniProt
site_idPS00601
Number of Residues34
DetailsIRF_1 IRF tryptophan pentad repeat DNA-binding domain signature. WeNeeksiFrIPWkHagkqdynreeDaaLFKaWA
ChainResidueDetails
ATRP27-ALA60

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues108
DetailsDNA binding: {"description":"IRF tryptophan pentad repeat","evidences":[{"source":"PROSITE-ProRule","id":"PRU00840","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

249697

PDB entries from 2026-02-25

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