2DHR
Whole cytosolic region of ATP-dependent metalloprotease FtsH (G399L)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004176 | molecular_function | ATP-dependent peptidase activity |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006508 | biological_process | proteolysis |
| A | 0016020 | cellular_component | membrane |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0004176 | molecular_function | ATP-dependent peptidase activity |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006508 | biological_process | proteolysis |
| B | 0016020 | cellular_component | membrane |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0004176 | molecular_function | ATP-dependent peptidase activity |
| C | 0004222 | molecular_function | metalloendopeptidase activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006508 | biological_process | proteolysis |
| C | 0016020 | cellular_component | membrane |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0004176 | molecular_function | ATP-dependent peptidase activity |
| D | 0004222 | molecular_function | metalloendopeptidase activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006508 | biological_process | proteolysis |
| D | 0016020 | cellular_component | membrane |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0004176 | molecular_function | ATP-dependent peptidase activity |
| E | 0004222 | molecular_function | metalloendopeptidase activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0006508 | biological_process | proteolysis |
| E | 0016020 | cellular_component | membrane |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0004176 | molecular_function | ATP-dependent peptidase activity |
| F | 0004222 | molecular_function | metalloendopeptidase activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0006508 | biological_process | proteolysis |
| F | 0016020 | cellular_component | membrane |
| F | 0016887 | molecular_function | ATP hydrolysis activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADP A 1001 |
| Chain | Residue |
| A | GLY199 |
| A | ALA363 |
| A | GLU366 |
| A | VAL200 |
| A | GLY201 |
| A | LYS202 |
| A | THR203 |
| A | HIS204 |
| A | ARG207 |
| A | ILE334 |
| A | HIS338 |
| site_id | AC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE ADP B 2001 |
| Chain | Residue |
| B | VAL158 |
| B | ALA159 |
| B | PRO197 |
| B | PRO198 |
| B | GLY199 |
| B | VAL200 |
| B | GLY201 |
| B | LYS202 |
| B | THR203 |
| B | HIS204 |
| B | ILE334 |
| B | GLU366 |
| site_id | AC3 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADP C 3001 |
| Chain | Residue |
| C | GLY199 |
| C | VAL200 |
| C | GLY201 |
| C | LYS202 |
| C | THR203 |
| C | HIS204 |
| C | ARG207 |
| C | ILE334 |
| C | HIS338 |
| C | ALA363 |
| C | GLU366 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP D 4001 |
| Chain | Residue |
| D | VAL158 |
| D | ALA159 |
| D | PRO197 |
| D | PRO198 |
| D | GLY199 |
| D | VAL200 |
| D | GLY201 |
| D | LYS202 |
| D | THR203 |
| D | HIS204 |
| D | ILE334 |
| D | HIS338 |
| D | ALA363 |
| D | GLU366 |
| site_id | AC5 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE ADP E 5001 |
| Chain | Residue |
| E | GLY199 |
| E | VAL200 |
| E | GLY201 |
| E | LYS202 |
| E | THR203 |
| E | HIS204 |
| E | ARG207 |
| E | ILE334 |
| E | HIS338 |
| E | ALA363 |
| E | GLU366 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ADP F 6001 |
| Chain | Residue |
| F | VAL158 |
| F | ALA159 |
| F | PRO197 |
| F | PRO198 |
| F | GLY199 |
| F | VAL200 |
| F | GLY201 |
| F | LYS202 |
| F | THR203 |
| F | HIS204 |
| F | ILE334 |
| F | HIS338 |
| F | ALA363 |
| F | GLU366 |
Functional Information from PROSITE/UniProt
| site_id | PS00674 |
| Number of Residues | 19 |
| Details | AAA AAA-protein family signature. IvVMaATNrpdiLDpALl.R |
| Chain | Residue | Details |
| A | ILE295-ARG313 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01458","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 36 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01458","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
