Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2DG2

Crystal Structure of Mouse Apolipoprotein A-I Binding Protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0002040	biological_process	sprouting angiogenesis
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0005739	cellular_component	mitochondrion
A	0005929	cellular_component	cilium
A	0006869	biological_process	lipid transport
A	0010874	biological_process	regulation of cholesterol efflux
A	0016525	biological_process	negative regulation of angiogenesis
A	0016853	molecular_function	isomerase activity
A	0031580	biological_process	membrane raft distribution
A	0042802	molecular_function	identical protein binding
A	0044297	cellular_component	cell body
A	0046496	biological_process	nicotinamide nucleotide metabolic process
A	0046872	molecular_function	metal ion binding
A	0052856	molecular_function	NADHX epimerase activity
A	0052857	molecular_function	NADPHX epimerase activity
B	0000166	molecular_function	nucleotide binding
B	0002040	biological_process	sprouting angiogenesis
B	0005576	cellular_component	extracellular region
B	0005615	cellular_component	extracellular space
B	0005739	cellular_component	mitochondrion
B	0005929	cellular_component	cilium
B	0006869	biological_process	lipid transport
B	0010874	biological_process	regulation of cholesterol efflux
B	0016525	biological_process	negative regulation of angiogenesis
B	0016853	molecular_function	isomerase activity
B	0031580	biological_process	membrane raft distribution
B	0042802	molecular_function	identical protein binding
B	0044297	cellular_component	cell body
B	0046496	biological_process	nicotinamide nucleotide metabolic process
B	0046872	molecular_function	metal ion binding
B	0052856	molecular_function	NADHX epimerase activity
B	0052857	molecular_function	NADPHX epimerase activity
C	0000166	molecular_function	nucleotide binding
C	0002040	biological_process	sprouting angiogenesis
C	0005576	cellular_component	extracellular region
C	0005615	cellular_component	extracellular space
C	0005739	cellular_component	mitochondrion
C	0005929	cellular_component	cilium
C	0006869	biological_process	lipid transport
C	0010874	biological_process	regulation of cholesterol efflux
C	0016525	biological_process	negative regulation of angiogenesis
C	0016853	molecular_function	isomerase activity
C	0031580	biological_process	membrane raft distribution
C	0042802	molecular_function	identical protein binding
C	0044297	cellular_component	cell body
C	0046496	biological_process	nicotinamide nucleotide metabolic process
C	0046872	molecular_function	metal ion binding
C	0052856	molecular_function	NADHX epimerase activity
C	0052857	molecular_function	NADPHX epimerase activity
D	0000166	molecular_function	nucleotide binding
D	0002040	biological_process	sprouting angiogenesis
D	0005576	cellular_component	extracellular region
D	0005615	cellular_component	extracellular space
D	0005739	cellular_component	mitochondrion
D	0005929	cellular_component	cilium
D	0006869	biological_process	lipid transport
D	0010874	biological_process	regulation of cholesterol efflux
D	0016525	biological_process	negative regulation of angiogenesis
D	0016853	molecular_function	isomerase activity
D	0031580	biological_process	membrane raft distribution
D	0042802	molecular_function	identical protein binding
D	0044297	cellular_component	cell body
D	0046496	biological_process	nicotinamide nucleotide metabolic process
D	0046872	molecular_function	metal ion binding
D	0052856	molecular_function	NADHX epimerase activity
D	0052857	molecular_function	NADPHX epimerase activity
E	0000166	molecular_function	nucleotide binding
E	0002040	biological_process	sprouting angiogenesis
E	0005576	cellular_component	extracellular region
E	0005615	cellular_component	extracellular space
E	0005739	cellular_component	mitochondrion
E	0005929	cellular_component	cilium
E	0006869	biological_process	lipid transport
E	0010874	biological_process	regulation of cholesterol efflux
E	0016525	biological_process	negative regulation of angiogenesis
E	0016853	molecular_function	isomerase activity
E	0031580	biological_process	membrane raft distribution
E	0042802	molecular_function	identical protein binding
E	0044297	cellular_component	cell body
E	0046496	biological_process	nicotinamide nucleotide metabolic process
E	0046872	molecular_function	metal ion binding
E	0052856	molecular_function	NADHX epimerase activity
E	0052857	molecular_function	NADPHX epimerase activity
F	0000166	molecular_function	nucleotide binding
F	0002040	biological_process	sprouting angiogenesis
F	0005576	cellular_component	extracellular region
F	0005615	cellular_component	extracellular space
F	0005739	cellular_component	mitochondrion
F	0005929	cellular_component	cilium
F	0006869	biological_process	lipid transport
F	0010874	biological_process	regulation of cholesterol efflux
F	0016525	biological_process	negative regulation of angiogenesis
F	0016853	molecular_function	isomerase activity
F	0031580	biological_process	membrane raft distribution
F	0042802	molecular_function	identical protein binding
F	0044297	cellular_component	cell body
F	0046496	biological_process	nicotinamide nucleotide metabolic process
F	0046872	molecular_function	metal ion binding
F	0052856	molecular_function	NADHX epimerase activity
F	0052857	molecular_function	NADPHX epimerase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 A 1001

Chain	Residue
A	GLY88
A	ASN89
A	ASN90
A	PHE158
A	GLY159
A	SER161
A	PHE162
A	HOH1034

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 1002

Chain	Residue
A	GLU168
A	ARG167

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE SO4 B 1003

Chain	Residue
B	GLY88
B	ASN89
B	ASN90
B	PHE158
B	GLY159
B	SER161
B	PHE162
B	HOH1020

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL B 1004

Chain	Residue
B	ARG167
B	GLU168

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 C 1005

Chain	Residue
C	GLY88
C	ASN89
C	ASN90
C	GLY159
C	PHE162
C	HOH1021
C	HOH1047

site_id	AC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL C 1006

Chain	Residue
C	ARG167
C	GLU168

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 D 1007

Chain	Residue
D	GLY88
D	ASN89
D	ASN90
D	PHE158
D	GLY159
D	SER161
D	PHE162

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL D 1008

Chain	Residue
D	ARG167
D	GLU168

site_id	AC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 E 1009

Chain	Residue
E	GLY88
E	ASN89
E	ASN90
E	PHE158
E	GLY159
E	SER161
E	PHE162

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL E 1010

Chain	Residue
E	ARG167
E	GLU168

site_id	BC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 F 1011

Chain	Residue
F	GLY88
F	ASN89
F	ASN90
F	PHE158
F	GLY159
F	SER161
F	PHE162

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL F 1012

Chain	Residue
F	ARG167
F	GLU168

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	36
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_03159

Chain	Residue	Details
A	ASN89
B	GLY159
B	ASP188
B	SER191
C	ASN89
C	ASN90
C	ASP155
C	GLY159
C	ASP188
C	SER191
D	ASN89
A	ASN90
D	ASN90
D	ASP155
D	GLY159
D	ASP188
D	SER191
E	ASN89
E	ASN90
E	ASP155
E	GLY159
E	ASP188
A	ASP155
E	SER191
F	ASN89
F	ASN90
F	ASP155
F	GLY159
F	ASP188
F	SER191
A	GLY159
A	ASP188
A	SER191
B	ASN89
B	ASN90
B	ASP155

site_id	SWS_FT_FI2
Number of Residues	6
Details	MOD_RES: Phosphoserine; by PKA => ECO:0000269\|PubMed:18202122, ECO:0007744\|PubMed:19131326, ECO:0007744\|PubMed:21183079

Chain	Residue	Details
A	SER19
B	SER19
C	SER19
D	SER19
E	SER19
F	SER19

site_id	SWS_FT_FI3
Number of Residues	6
Details	MOD_RES: N6-succinyllysine => ECO:0007744\|PubMed:23806337

Chain	Residue	Details
A	LYS114
B	LYS114
C	LYS114
D	LYS114
E	LYS114
F	LYS114

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)