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2DFS

3-D structure of Myosin-V inhibited state

Functional Information from GO Data
ChainGOidnamespacecontents
A0003774molecular_functioncytoskeletal motor activity
A0005524molecular_functionATP binding
A0016459cellular_componentmyosin complex
B0000086biological_processG2/M transition of mitotic cell cycle
B0000922cellular_componentspindle pole
B0001975biological_processresponse to amphetamine
B0002027biological_processregulation of heart rate
B0005246molecular_functioncalcium channel regulator activity
B0005509molecular_functioncalcium ion binding
B0005513biological_processdetection of calcium ion
B0005515molecular_functionprotein binding
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005813cellular_componentcentrosome
B0005819cellular_componentspindle
B0005829cellular_componentcytosol
B0005856cellular_componentcytoskeleton
B0005876cellular_componentspindle microtubule
B0005929cellular_componentcilium
B0006897biological_processendocytosis
B0008076cellular_componentvoltage-gated potassium channel complex
B0008179molecular_functionadenylate cyclase binding
B0010856molecular_functionadenylate cyclase activator activity
B0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
B0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
B0016240biological_processautophagosome membrane docking
B0019855molecular_functioncalcium channel inhibitor activity
B0019901molecular_functionprotein kinase binding
B0019904molecular_functionprotein domain specific binding
B0030017cellular_componentsarcomere
B0030235molecular_functionnitric-oxide synthase regulator activity
B0030426cellular_componentgrowth cone
B0030672cellular_componentsynaptic vesicle membrane
B0031432molecular_functiontitin binding
B0031514cellular_componentmotile cilium
B0031800molecular_functiontype 3 metabotropic glutamate receptor binding
B0031966cellular_componentmitochondrial membrane
B0032465biological_processregulation of cytokinesis
B0032991cellular_componentprotein-containing complex
B0034704cellular_componentcalcium channel complex
B0035458biological_processcellular response to interferon-beta
B0042995cellular_componentcell projection
B0043209cellular_componentmyelin sheath
B0043539molecular_functionprotein serine/threonine kinase activator activity
B0043548molecular_functionphosphatidylinositol 3-kinase binding
B0044305cellular_componentcalyx of Held
B0044325molecular_functiontransmembrane transporter binding
B0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
B0046872molecular_functionmetal ion binding
B0048306molecular_functioncalcium-dependent protein binding
B0050998molecular_functionnitric-oxide synthase binding
B0051412biological_processresponse to corticosterone
B0051592biological_processresponse to calcium ion
B0051649biological_processestablishment of localization in cell
B0055117biological_processregulation of cardiac muscle contraction
B0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
B0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
B0071346biological_processcellular response to type II interferon
B0072542molecular_functionprotein phosphatase activator activity
B0090150biological_processestablishment of protein localization to membrane
B0090151biological_processestablishment of protein localization to mitochondrial membrane
B0097225cellular_componentsperm midpiece
B0097720biological_processcalcineurin-mediated signaling
B0098685cellular_componentSchaffer collateral - CA1 synapse
B0098901biological_processregulation of cardiac muscle cell action potential
B0099523cellular_componentpresynaptic cytosol
B0099524cellular_componentpostsynaptic cytosol
B0140056biological_processorganelle localization by membrane tethering
B0140238biological_processpresynaptic endocytosis
B0150034cellular_componentdistal axon
B1900242biological_processregulation of synaptic vesicle endocytosis
B1902494cellular_componentcatalytic complex
B1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
B2000300biological_processregulation of synaptic vesicle exocytosis
C0000086biological_processG2/M transition of mitotic cell cycle
C0000922cellular_componentspindle pole
C0001975biological_processresponse to amphetamine
C0002027biological_processregulation of heart rate
C0005246molecular_functioncalcium channel regulator activity
C0005509molecular_functioncalcium ion binding
C0005513biological_processdetection of calcium ion
C0005515molecular_functionprotein binding
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005813cellular_componentcentrosome
C0005819cellular_componentspindle
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005876cellular_componentspindle microtubule
C0005929cellular_componentcilium
C0006897biological_processendocytosis
C0008076cellular_componentvoltage-gated potassium channel complex
C0008179molecular_functionadenylate cyclase binding
C0010856molecular_functionadenylate cyclase activator activity
C0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
C0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
C0016240biological_processautophagosome membrane docking
C0019855molecular_functioncalcium channel inhibitor activity
C0019901molecular_functionprotein kinase binding
C0019904molecular_functionprotein domain specific binding
C0030017cellular_componentsarcomere
C0030235molecular_functionnitric-oxide synthase regulator activity
C0030426cellular_componentgrowth cone
C0030672cellular_componentsynaptic vesicle membrane
C0031432molecular_functiontitin binding
C0031514cellular_componentmotile cilium
C0031800molecular_functiontype 3 metabotropic glutamate receptor binding
C0031966cellular_componentmitochondrial membrane
C0032465biological_processregulation of cytokinesis
C0032991cellular_componentprotein-containing complex
C0034704cellular_componentcalcium channel complex
C0035458biological_processcellular response to interferon-beta
C0042995cellular_componentcell projection
C0043209cellular_componentmyelin sheath
C0043539molecular_functionprotein serine/threonine kinase activator activity
C0043548molecular_functionphosphatidylinositol 3-kinase binding
C0044305cellular_componentcalyx of Held
C0044325molecular_functiontransmembrane transporter binding
C0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
C0046872molecular_functionmetal ion binding
C0048306molecular_functioncalcium-dependent protein binding
C0050998molecular_functionnitric-oxide synthase binding
C0051412biological_processresponse to corticosterone
C0051592biological_processresponse to calcium ion
C0051649biological_processestablishment of localization in cell
C0055117biological_processregulation of cardiac muscle contraction
C0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
C0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
C0071346biological_processcellular response to type II interferon
C0072542molecular_functionprotein phosphatase activator activity
C0090150biological_processestablishment of protein localization to membrane
C0090151biological_processestablishment of protein localization to mitochondrial membrane
C0097225cellular_componentsperm midpiece
C0097720biological_processcalcineurin-mediated signaling
C0098685cellular_componentSchaffer collateral - CA1 synapse
C0098901biological_processregulation of cardiac muscle cell action potential
C0099523cellular_componentpresynaptic cytosol
C0099524cellular_componentpostsynaptic cytosol
C0140056biological_processorganelle localization by membrane tethering
C0140238biological_processpresynaptic endocytosis
C0150034cellular_componentdistal axon
C1900242biological_processregulation of synaptic vesicle endocytosis
C1902494cellular_componentcatalytic complex
C1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
C2000300biological_processregulation of synaptic vesicle exocytosis
D0000086biological_processG2/M transition of mitotic cell cycle
D0000922cellular_componentspindle pole
D0001975biological_processresponse to amphetamine
D0002027biological_processregulation of heart rate
D0005246molecular_functioncalcium channel regulator activity
D0005509molecular_functioncalcium ion binding
D0005513biological_processdetection of calcium ion
D0005515molecular_functionprotein binding
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005813cellular_componentcentrosome
D0005819cellular_componentspindle
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005876cellular_componentspindle microtubule
D0005929cellular_componentcilium
D0006897biological_processendocytosis
D0008076cellular_componentvoltage-gated potassium channel complex
D0008179molecular_functionadenylate cyclase binding
D0010856molecular_functionadenylate cyclase activator activity
D0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
D0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
D0016240biological_processautophagosome membrane docking
D0019855molecular_functioncalcium channel inhibitor activity
D0019901molecular_functionprotein kinase binding
D0019904molecular_functionprotein domain specific binding
D0030017cellular_componentsarcomere
D0030235molecular_functionnitric-oxide synthase regulator activity
D0030426cellular_componentgrowth cone
D0030672cellular_componentsynaptic vesicle membrane
D0031432molecular_functiontitin binding
D0031514cellular_componentmotile cilium
D0031800molecular_functiontype 3 metabotropic glutamate receptor binding
D0031966cellular_componentmitochondrial membrane
D0032465biological_processregulation of cytokinesis
D0032991cellular_componentprotein-containing complex
D0034704cellular_componentcalcium channel complex
D0035458biological_processcellular response to interferon-beta
D0042995cellular_componentcell projection
D0043209cellular_componentmyelin sheath
D0043539molecular_functionprotein serine/threonine kinase activator activity
D0043548molecular_functionphosphatidylinositol 3-kinase binding
D0044305cellular_componentcalyx of Held
D0044325molecular_functiontransmembrane transporter binding
D0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
D0046872molecular_functionmetal ion binding
D0048306molecular_functioncalcium-dependent protein binding
D0050998molecular_functionnitric-oxide synthase binding
D0051412biological_processresponse to corticosterone
D0051592biological_processresponse to calcium ion
D0051649biological_processestablishment of localization in cell
D0055117biological_processregulation of cardiac muscle contraction
D0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
D0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
D0071346biological_processcellular response to type II interferon
D0072542molecular_functionprotein phosphatase activator activity
D0090150biological_processestablishment of protein localization to membrane
D0090151biological_processestablishment of protein localization to mitochondrial membrane
D0097225cellular_componentsperm midpiece
D0097720biological_processcalcineurin-mediated signaling
D0098685cellular_componentSchaffer collateral - CA1 synapse
D0098901biological_processregulation of cardiac muscle cell action potential
D0099523cellular_componentpresynaptic cytosol
D0099524cellular_componentpostsynaptic cytosol
D0140056biological_processorganelle localization by membrane tethering
D0140238biological_processpresynaptic endocytosis
D0150034cellular_componentdistal axon
D1900242biological_processregulation of synaptic vesicle endocytosis
D1902494cellular_componentcatalytic complex
D1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
D2000300biological_processregulation of synaptic vesicle exocytosis
E0000086biological_processG2/M transition of mitotic cell cycle
E0000922cellular_componentspindle pole
E0001975biological_processresponse to amphetamine
E0002027biological_processregulation of heart rate
E0005246molecular_functioncalcium channel regulator activity
E0005509molecular_functioncalcium ion binding
E0005513biological_processdetection of calcium ion
E0005515molecular_functionprotein binding
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005739cellular_componentmitochondrion
E0005813cellular_componentcentrosome
E0005819cellular_componentspindle
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005876cellular_componentspindle microtubule
E0005929cellular_componentcilium
E0006897biological_processendocytosis
E0008076cellular_componentvoltage-gated potassium channel complex
E0008179molecular_functionadenylate cyclase binding
E0010856molecular_functionadenylate cyclase activator activity
E0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
E0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
E0016240biological_processautophagosome membrane docking
E0019855molecular_functioncalcium channel inhibitor activity
E0019901molecular_functionprotein kinase binding
E0019904molecular_functionprotein domain specific binding
E0030017cellular_componentsarcomere
E0030235molecular_functionnitric-oxide synthase regulator activity
E0030426cellular_componentgrowth cone
E0030672cellular_componentsynaptic vesicle membrane
E0031432molecular_functiontitin binding
E0031514cellular_componentmotile cilium
E0031800molecular_functiontype 3 metabotropic glutamate receptor binding
E0031966cellular_componentmitochondrial membrane
E0032465biological_processregulation of cytokinesis
E0032991cellular_componentprotein-containing complex
E0034704cellular_componentcalcium channel complex
E0035458biological_processcellular response to interferon-beta
E0042995cellular_componentcell projection
E0043209cellular_componentmyelin sheath
E0043539molecular_functionprotein serine/threonine kinase activator activity
E0043548molecular_functionphosphatidylinositol 3-kinase binding
E0044305cellular_componentcalyx of Held
E0044325molecular_functiontransmembrane transporter binding
E0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
E0046872molecular_functionmetal ion binding
E0048306molecular_functioncalcium-dependent protein binding
E0050998molecular_functionnitric-oxide synthase binding
E0051412biological_processresponse to corticosterone
E0051592biological_processresponse to calcium ion
E0051649biological_processestablishment of localization in cell
E0055117biological_processregulation of cardiac muscle contraction
E0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
E0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
E0071346biological_processcellular response to type II interferon
E0072542molecular_functionprotein phosphatase activator activity
E0090150biological_processestablishment of protein localization to membrane
E0090151biological_processestablishment of protein localization to mitochondrial membrane
E0097225cellular_componentsperm midpiece
E0097720biological_processcalcineurin-mediated signaling
E0098685cellular_componentSchaffer collateral - CA1 synapse
E0098901biological_processregulation of cardiac muscle cell action potential
E0099523cellular_componentpresynaptic cytosol
E0099524cellular_componentpostsynaptic cytosol
E0140056biological_processorganelle localization by membrane tethering
E0140238biological_processpresynaptic endocytosis
E0150034cellular_componentdistal axon
E1900242biological_processregulation of synaptic vesicle endocytosis
E1902494cellular_componentcatalytic complex
E1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
E2000300biological_processregulation of synaptic vesicle exocytosis
F0000086biological_processG2/M transition of mitotic cell cycle
F0000922cellular_componentspindle pole
F0001975biological_processresponse to amphetamine
F0002027biological_processregulation of heart rate
F0005246molecular_functioncalcium channel regulator activity
F0005509molecular_functioncalcium ion binding
F0005513biological_processdetection of calcium ion
F0005515molecular_functionprotein binding
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005813cellular_componentcentrosome
F0005819cellular_componentspindle
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005876cellular_componentspindle microtubule
F0005929cellular_componentcilium
F0006897biological_processendocytosis
F0008076cellular_componentvoltage-gated potassium channel complex
F0008179molecular_functionadenylate cyclase binding
F0010856molecular_functionadenylate cyclase activator activity
F0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
F0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
F0016240biological_processautophagosome membrane docking
F0019855molecular_functioncalcium channel inhibitor activity
F0019901molecular_functionprotein kinase binding
F0019904molecular_functionprotein domain specific binding
F0030017cellular_componentsarcomere
F0030235molecular_functionnitric-oxide synthase regulator activity
F0030426cellular_componentgrowth cone
F0030672cellular_componentsynaptic vesicle membrane
F0031432molecular_functiontitin binding
F0031514cellular_componentmotile cilium
F0031800molecular_functiontype 3 metabotropic glutamate receptor binding
F0031966cellular_componentmitochondrial membrane
F0032465biological_processregulation of cytokinesis
F0032991cellular_componentprotein-containing complex
F0034704cellular_componentcalcium channel complex
F0035458biological_processcellular response to interferon-beta
F0042995cellular_componentcell projection
F0043209cellular_componentmyelin sheath
F0043539molecular_functionprotein serine/threonine kinase activator activity
F0043548molecular_functionphosphatidylinositol 3-kinase binding
F0044305cellular_componentcalyx of Held
F0044325molecular_functiontransmembrane transporter binding
F0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
F0046872molecular_functionmetal ion binding
F0048306molecular_functioncalcium-dependent protein binding
F0050998molecular_functionnitric-oxide synthase binding
F0051412biological_processresponse to corticosterone
F0051592biological_processresponse to calcium ion
F0051649biological_processestablishment of localization in cell
F0055117biological_processregulation of cardiac muscle contraction
F0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
F0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
F0071346biological_processcellular response to type II interferon
F0072542molecular_functionprotein phosphatase activator activity
F0090150biological_processestablishment of protein localization to membrane
F0090151biological_processestablishment of protein localization to mitochondrial membrane
F0097225cellular_componentsperm midpiece
F0097720biological_processcalcineurin-mediated signaling
F0098685cellular_componentSchaffer collateral - CA1 synapse
F0098901biological_processregulation of cardiac muscle cell action potential
F0099523cellular_componentpresynaptic cytosol
F0099524cellular_componentpostsynaptic cytosol
F0140056biological_processorganelle localization by membrane tethering
F0140238biological_processpresynaptic endocytosis
F0150034cellular_componentdistal axon
F1900242biological_processregulation of synaptic vesicle endocytosis
F1902494cellular_componentcatalytic complex
F1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
F2000300biological_processregulation of synaptic vesicle exocytosis
G0000086biological_processG2/M transition of mitotic cell cycle
G0000922cellular_componentspindle pole
G0001975biological_processresponse to amphetamine
G0002027biological_processregulation of heart rate
G0005246molecular_functioncalcium channel regulator activity
G0005509molecular_functioncalcium ion binding
G0005513biological_processdetection of calcium ion
G0005515molecular_functionprotein binding
G0005654cellular_componentnucleoplasm
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005813cellular_componentcentrosome
G0005819cellular_componentspindle
G0005829cellular_componentcytosol
G0005856cellular_componentcytoskeleton
G0005876cellular_componentspindle microtubule
G0005929cellular_componentcilium
G0006897biological_processendocytosis
G0008076cellular_componentvoltage-gated potassium channel complex
G0008179molecular_functionadenylate cyclase binding
G0010856molecular_functionadenylate cyclase activator activity
G0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
G0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
G0016240biological_processautophagosome membrane docking
G0019855molecular_functioncalcium channel inhibitor activity
G0019901molecular_functionprotein kinase binding
G0019904molecular_functionprotein domain specific binding
G0030017cellular_componentsarcomere
G0030235molecular_functionnitric-oxide synthase regulator activity
G0030426cellular_componentgrowth cone
G0030672cellular_componentsynaptic vesicle membrane
G0031432molecular_functiontitin binding
G0031514cellular_componentmotile cilium
G0031800molecular_functiontype 3 metabotropic glutamate receptor binding
G0031966cellular_componentmitochondrial membrane
G0032465biological_processregulation of cytokinesis
G0032991cellular_componentprotein-containing complex
G0034704cellular_componentcalcium channel complex
G0035458biological_processcellular response to interferon-beta
G0042995cellular_componentcell projection
G0043209cellular_componentmyelin sheath
G0043539molecular_functionprotein serine/threonine kinase activator activity
G0043548molecular_functionphosphatidylinositol 3-kinase binding
G0044305cellular_componentcalyx of Held
G0044325molecular_functiontransmembrane transporter binding
G0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
G0046872molecular_functionmetal ion binding
G0048306molecular_functioncalcium-dependent protein binding
G0050998molecular_functionnitric-oxide synthase binding
G0051412biological_processresponse to corticosterone
G0051592biological_processresponse to calcium ion
G0051649biological_processestablishment of localization in cell
G0055117biological_processregulation of cardiac muscle contraction
G0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
G0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
G0071346biological_processcellular response to type II interferon
G0072542molecular_functionprotein phosphatase activator activity
G0090150biological_processestablishment of protein localization to membrane
G0090151biological_processestablishment of protein localization to mitochondrial membrane
G0097225cellular_componentsperm midpiece
G0097720biological_processcalcineurin-mediated signaling
G0098685cellular_componentSchaffer collateral - CA1 synapse
G0098901biological_processregulation of cardiac muscle cell action potential
G0099523cellular_componentpresynaptic cytosol
G0099524cellular_componentpostsynaptic cytosol
G0140056biological_processorganelle localization by membrane tethering
G0140238biological_processpresynaptic endocytosis
G0150034cellular_componentdistal axon
G1900242biological_processregulation of synaptic vesicle endocytosis
G1902494cellular_componentcatalytic complex
G1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
G2000300biological_processregulation of synaptic vesicle exocytosis
M0003774molecular_functioncytoskeletal motor activity
M0005524molecular_functionATP binding
M0016459cellular_componentmyosin complex
N0000086biological_processG2/M transition of mitotic cell cycle
N0000922cellular_componentspindle pole
N0001975biological_processresponse to amphetamine
N0002027biological_processregulation of heart rate
N0005246molecular_functioncalcium channel regulator activity
N0005509molecular_functioncalcium ion binding
N0005513biological_processdetection of calcium ion
N0005515molecular_functionprotein binding
N0005654cellular_componentnucleoplasm
N0005737cellular_componentcytoplasm
N0005739cellular_componentmitochondrion
N0005813cellular_componentcentrosome
N0005819cellular_componentspindle
N0005829cellular_componentcytosol
N0005856cellular_componentcytoskeleton
N0005876cellular_componentspindle microtubule
N0005929cellular_componentcilium
N0006897biological_processendocytosis
N0008076cellular_componentvoltage-gated potassium channel complex
N0008179molecular_functionadenylate cyclase binding
N0010856molecular_functionadenylate cyclase activator activity
N0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
N0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
N0016240biological_processautophagosome membrane docking
N0019855molecular_functioncalcium channel inhibitor activity
N0019901molecular_functionprotein kinase binding
N0019904molecular_functionprotein domain specific binding
N0030017cellular_componentsarcomere
N0030235molecular_functionnitric-oxide synthase regulator activity
N0030426cellular_componentgrowth cone
N0030672cellular_componentsynaptic vesicle membrane
N0031432molecular_functiontitin binding
N0031514cellular_componentmotile cilium
N0031800molecular_functiontype 3 metabotropic glutamate receptor binding
N0031966cellular_componentmitochondrial membrane
N0032465biological_processregulation of cytokinesis
N0032991cellular_componentprotein-containing complex
N0034704cellular_componentcalcium channel complex
N0035458biological_processcellular response to interferon-beta
N0042995cellular_componentcell projection
N0043209cellular_componentmyelin sheath
N0043539molecular_functionprotein serine/threonine kinase activator activity
N0043548molecular_functionphosphatidylinositol 3-kinase binding
N0044305cellular_componentcalyx of Held
N0044325molecular_functiontransmembrane transporter binding
N0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
N0046872molecular_functionmetal ion binding
N0048306molecular_functioncalcium-dependent protein binding
N0050998molecular_functionnitric-oxide synthase binding
N0051412biological_processresponse to corticosterone
N0051592biological_processresponse to calcium ion
N0051649biological_processestablishment of localization in cell
N0055117biological_processregulation of cardiac muscle contraction
N0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
N0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
N0071346biological_processcellular response to type II interferon
N0072542molecular_functionprotein phosphatase activator activity
N0090150biological_processestablishment of protein localization to membrane
N0090151biological_processestablishment of protein localization to mitochondrial membrane
N0097225cellular_componentsperm midpiece
N0097720biological_processcalcineurin-mediated signaling
N0098685cellular_componentSchaffer collateral - CA1 synapse
N0098901biological_processregulation of cardiac muscle cell action potential
N0099523cellular_componentpresynaptic cytosol
N0099524cellular_componentpostsynaptic cytosol
N0140056biological_processorganelle localization by membrane tethering
N0140238biological_processpresynaptic endocytosis
N0150034cellular_componentdistal axon
N1900242biological_processregulation of synaptic vesicle endocytosis
N1902494cellular_componentcatalytic complex
N1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
N2000300biological_processregulation of synaptic vesicle exocytosis
O0000086biological_processG2/M transition of mitotic cell cycle
O0000922cellular_componentspindle pole
O0001975biological_processresponse to amphetamine
O0002027biological_processregulation of heart rate
O0005246molecular_functioncalcium channel regulator activity
O0005509molecular_functioncalcium ion binding
O0005513biological_processdetection of calcium ion
O0005515molecular_functionprotein binding
O0005654cellular_componentnucleoplasm
O0005737cellular_componentcytoplasm
O0005739cellular_componentmitochondrion
O0005813cellular_componentcentrosome
O0005819cellular_componentspindle
O0005829cellular_componentcytosol
O0005856cellular_componentcytoskeleton
O0005876cellular_componentspindle microtubule
O0005929cellular_componentcilium
O0006897biological_processendocytosis
O0008076cellular_componentvoltage-gated potassium channel complex
O0008179molecular_functionadenylate cyclase binding
O0010856molecular_functionadenylate cyclase activator activity
O0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
O0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
O0016240biological_processautophagosome membrane docking
O0019855molecular_functioncalcium channel inhibitor activity
O0019901molecular_functionprotein kinase binding
O0019904molecular_functionprotein domain specific binding
O0030017cellular_componentsarcomere
O0030235molecular_functionnitric-oxide synthase regulator activity
O0030426cellular_componentgrowth cone
O0030672cellular_componentsynaptic vesicle membrane
O0031432molecular_functiontitin binding
O0031514cellular_componentmotile cilium
O0031800molecular_functiontype 3 metabotropic glutamate receptor binding
O0031966cellular_componentmitochondrial membrane
O0032465biological_processregulation of cytokinesis
O0032991cellular_componentprotein-containing complex
O0034704cellular_componentcalcium channel complex
O0035458biological_processcellular response to interferon-beta
O0042995cellular_componentcell projection
O0043209cellular_componentmyelin sheath
O0043539molecular_functionprotein serine/threonine kinase activator activity
O0043548molecular_functionphosphatidylinositol 3-kinase binding
O0044305cellular_componentcalyx of Held
O0044325molecular_functiontransmembrane transporter binding
O0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
O0046872molecular_functionmetal ion binding
O0048306molecular_functioncalcium-dependent protein binding
O0050998molecular_functionnitric-oxide synthase binding
O0051412biological_processresponse to corticosterone
O0051592biological_processresponse to calcium ion
O0051649biological_processestablishment of localization in cell
O0055117biological_processregulation of cardiac muscle contraction
O0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
O0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
O0071346biological_processcellular response to type II interferon
O0072542molecular_functionprotein phosphatase activator activity
O0090150biological_processestablishment of protein localization to membrane
O0090151biological_processestablishment of protein localization to mitochondrial membrane
O0097225cellular_componentsperm midpiece
O0097720biological_processcalcineurin-mediated signaling
O0098685cellular_componentSchaffer collateral - CA1 synapse
O0098901biological_processregulation of cardiac muscle cell action potential
O0099523cellular_componentpresynaptic cytosol
O0099524cellular_componentpostsynaptic cytosol
O0140056biological_processorganelle localization by membrane tethering
O0140238biological_processpresynaptic endocytosis
O0150034cellular_componentdistal axon
O1900242biological_processregulation of synaptic vesicle endocytosis
O1902494cellular_componentcatalytic complex
O1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
O2000300biological_processregulation of synaptic vesicle exocytosis
P0000086biological_processG2/M transition of mitotic cell cycle
P0000922cellular_componentspindle pole
P0001975biological_processresponse to amphetamine
P0002027biological_processregulation of heart rate
P0005246molecular_functioncalcium channel regulator activity
P0005509molecular_functioncalcium ion binding
P0005513biological_processdetection of calcium ion
P0005515molecular_functionprotein binding
P0005654cellular_componentnucleoplasm
P0005737cellular_componentcytoplasm
P0005739cellular_componentmitochondrion
P0005813cellular_componentcentrosome
P0005819cellular_componentspindle
P0005829cellular_componentcytosol
P0005856cellular_componentcytoskeleton
P0005876cellular_componentspindle microtubule
P0005929cellular_componentcilium
P0006897biological_processendocytosis
P0008076cellular_componentvoltage-gated potassium channel complex
P0008179molecular_functionadenylate cyclase binding
P0010856molecular_functionadenylate cyclase activator activity
P0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
P0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
P0016240biological_processautophagosome membrane docking
P0019855molecular_functioncalcium channel inhibitor activity
P0019901molecular_functionprotein kinase binding
P0019904molecular_functionprotein domain specific binding
P0030017cellular_componentsarcomere
P0030235molecular_functionnitric-oxide synthase regulator activity
P0030426cellular_componentgrowth cone
P0030672cellular_componentsynaptic vesicle membrane
P0031432molecular_functiontitin binding
P0031514cellular_componentmotile cilium
P0031800molecular_functiontype 3 metabotropic glutamate receptor binding
P0031966cellular_componentmitochondrial membrane
P0032465biological_processregulation of cytokinesis
P0032991cellular_componentprotein-containing complex
P0034704cellular_componentcalcium channel complex
P0035458biological_processcellular response to interferon-beta
P0042995cellular_componentcell projection
P0043209cellular_componentmyelin sheath
P0043539molecular_functionprotein serine/threonine kinase activator activity
P0043548molecular_functionphosphatidylinositol 3-kinase binding
P0044305cellular_componentcalyx of Held
P0044325molecular_functiontransmembrane transporter binding
P0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
P0046872molecular_functionmetal ion binding
P0048306molecular_functioncalcium-dependent protein binding
P0050998molecular_functionnitric-oxide synthase binding
P0051412biological_processresponse to corticosterone
P0051592biological_processresponse to calcium ion
P0051649biological_processestablishment of localization in cell
P0055117biological_processregulation of cardiac muscle contraction
P0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
P0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
P0071346biological_processcellular response to type II interferon
P0072542molecular_functionprotein phosphatase activator activity
P0090150biological_processestablishment of protein localization to membrane
P0090151biological_processestablishment of protein localization to mitochondrial membrane
P0097225cellular_componentsperm midpiece
P0097720biological_processcalcineurin-mediated signaling
P0098685cellular_componentSchaffer collateral - CA1 synapse
P0098901biological_processregulation of cardiac muscle cell action potential
P0099523cellular_componentpresynaptic cytosol
P0099524cellular_componentpostsynaptic cytosol
P0140056biological_processorganelle localization by membrane tethering
P0140238biological_processpresynaptic endocytosis
P0150034cellular_componentdistal axon
P1900242biological_processregulation of synaptic vesicle endocytosis
P1902494cellular_componentcatalytic complex
P1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
P2000300biological_processregulation of synaptic vesicle exocytosis
Q0000086biological_processG2/M transition of mitotic cell cycle
Q0000922cellular_componentspindle pole
Q0001975biological_processresponse to amphetamine
Q0002027biological_processregulation of heart rate
Q0005246molecular_functioncalcium channel regulator activity
Q0005509molecular_functioncalcium ion binding
Q0005513biological_processdetection of calcium ion
Q0005515molecular_functionprotein binding
Q0005654cellular_componentnucleoplasm
Q0005737cellular_componentcytoplasm
Q0005739cellular_componentmitochondrion
Q0005813cellular_componentcentrosome
Q0005819cellular_componentspindle
Q0005829cellular_componentcytosol
Q0005856cellular_componentcytoskeleton
Q0005876cellular_componentspindle microtubule
Q0005929cellular_componentcilium
Q0006897biological_processendocytosis
Q0008076cellular_componentvoltage-gated potassium channel complex
Q0008179molecular_functionadenylate cyclase binding
Q0010856molecular_functionadenylate cyclase activator activity
Q0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
Q0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
Q0016240biological_processautophagosome membrane docking
Q0019855molecular_functioncalcium channel inhibitor activity
Q0019901molecular_functionprotein kinase binding
Q0019904molecular_functionprotein domain specific binding
Q0030017cellular_componentsarcomere
Q0030235molecular_functionnitric-oxide synthase regulator activity
Q0030426cellular_componentgrowth cone
Q0030672cellular_componentsynaptic vesicle membrane
Q0031432molecular_functiontitin binding
Q0031514cellular_componentmotile cilium
Q0031800molecular_functiontype 3 metabotropic glutamate receptor binding
Q0031966cellular_componentmitochondrial membrane
Q0032465biological_processregulation of cytokinesis
Q0032991cellular_componentprotein-containing complex
Q0034704cellular_componentcalcium channel complex
Q0035458biological_processcellular response to interferon-beta
Q0042995cellular_componentcell projection
Q0043209cellular_componentmyelin sheath
Q0043539molecular_functionprotein serine/threonine kinase activator activity
Q0043548molecular_functionphosphatidylinositol 3-kinase binding
Q0044305cellular_componentcalyx of Held
Q0044325molecular_functiontransmembrane transporter binding
Q0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
Q0046872molecular_functionmetal ion binding
Q0048306molecular_functioncalcium-dependent protein binding
Q0050998molecular_functionnitric-oxide synthase binding
Q0051412biological_processresponse to corticosterone
Q0051592biological_processresponse to calcium ion
Q0051649biological_processestablishment of localization in cell
Q0055117biological_processregulation of cardiac muscle contraction
Q0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
Q0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
Q0071346biological_processcellular response to type II interferon
Q0072542molecular_functionprotein phosphatase activator activity
Q0090150biological_processestablishment of protein localization to membrane
Q0090151biological_processestablishment of protein localization to mitochondrial membrane
Q0097225cellular_componentsperm midpiece
Q0097720biological_processcalcineurin-mediated signaling
Q0098685cellular_componentSchaffer collateral - CA1 synapse
Q0098901biological_processregulation of cardiac muscle cell action potential
Q0099523cellular_componentpresynaptic cytosol
Q0099524cellular_componentpostsynaptic cytosol
Q0140056biological_processorganelle localization by membrane tethering
Q0140238biological_processpresynaptic endocytosis
Q0150034cellular_componentdistal axon
Q1900242biological_processregulation of synaptic vesicle endocytosis
Q1902494cellular_componentcatalytic complex
Q1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
Q2000300biological_processregulation of synaptic vesicle exocytosis
R0000086biological_processG2/M transition of mitotic cell cycle
R0000922cellular_componentspindle pole
R0001975biological_processresponse to amphetamine
R0002027biological_processregulation of heart rate
R0005246molecular_functioncalcium channel regulator activity
R0005509molecular_functioncalcium ion binding
R0005513biological_processdetection of calcium ion
R0005515molecular_functionprotein binding
R0005654cellular_componentnucleoplasm
R0005737cellular_componentcytoplasm
R0005739cellular_componentmitochondrion
R0005813cellular_componentcentrosome
R0005819cellular_componentspindle
R0005829cellular_componentcytosol
R0005856cellular_componentcytoskeleton
R0005876cellular_componentspindle microtubule
R0005929cellular_componentcilium
R0006897biological_processendocytosis
R0008076cellular_componentvoltage-gated potassium channel complex
R0008179molecular_functionadenylate cyclase binding
R0010856molecular_functionadenylate cyclase activator activity
R0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
R0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
R0016240biological_processautophagosome membrane docking
R0019855molecular_functioncalcium channel inhibitor activity
R0019901molecular_functionprotein kinase binding
R0019904molecular_functionprotein domain specific binding
R0030017cellular_componentsarcomere
R0030235molecular_functionnitric-oxide synthase regulator activity
R0030426cellular_componentgrowth cone
R0030672cellular_componentsynaptic vesicle membrane
R0031432molecular_functiontitin binding
R0031514cellular_componentmotile cilium
R0031800molecular_functiontype 3 metabotropic glutamate receptor binding
R0031966cellular_componentmitochondrial membrane
R0032465biological_processregulation of cytokinesis
R0032991cellular_componentprotein-containing complex
R0034704cellular_componentcalcium channel complex
R0035458biological_processcellular response to interferon-beta
R0042995cellular_componentcell projection
R0043209cellular_componentmyelin sheath
R0043539molecular_functionprotein serine/threonine kinase activator activity
R0043548molecular_functionphosphatidylinositol 3-kinase binding
R0044305cellular_componentcalyx of Held
R0044325molecular_functiontransmembrane transporter binding
R0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
R0046872molecular_functionmetal ion binding
R0048306molecular_functioncalcium-dependent protein binding
R0050998molecular_functionnitric-oxide synthase binding
R0051412biological_processresponse to corticosterone
R0051592biological_processresponse to calcium ion
R0051649biological_processestablishment of localization in cell
R0055117biological_processregulation of cardiac muscle contraction
R0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
R0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
R0071346biological_processcellular response to type II interferon
R0072542molecular_functionprotein phosphatase activator activity
R0090150biological_processestablishment of protein localization to membrane
R0090151biological_processestablishment of protein localization to mitochondrial membrane
R0097225cellular_componentsperm midpiece
R0097720biological_processcalcineurin-mediated signaling
R0098685cellular_componentSchaffer collateral - CA1 synapse
R0098901biological_processregulation of cardiac muscle cell action potential
R0099523cellular_componentpresynaptic cytosol
R0099524cellular_componentpostsynaptic cytosol
R0140056biological_processorganelle localization by membrane tethering
R0140238biological_processpresynaptic endocytosis
R0150034cellular_componentdistal axon
R1900242biological_processregulation of synaptic vesicle endocytosis
R1902494cellular_componentcatalytic complex
R1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
R2000300biological_processregulation of synaptic vesicle exocytosis
S0000086biological_processG2/M transition of mitotic cell cycle
S0000922cellular_componentspindle pole
S0001975biological_processresponse to amphetamine
S0002027biological_processregulation of heart rate
S0005246molecular_functioncalcium channel regulator activity
S0005509molecular_functioncalcium ion binding
S0005513biological_processdetection of calcium ion
S0005515molecular_functionprotein binding
S0005654cellular_componentnucleoplasm
S0005737cellular_componentcytoplasm
S0005739cellular_componentmitochondrion
S0005813cellular_componentcentrosome
S0005819cellular_componentspindle
S0005829cellular_componentcytosol
S0005856cellular_componentcytoskeleton
S0005876cellular_componentspindle microtubule
S0005929cellular_componentcilium
S0006897biological_processendocytosis
S0008076cellular_componentvoltage-gated potassium channel complex
S0008179molecular_functionadenylate cyclase binding
S0010856molecular_functionadenylate cyclase activator activity
S0010880biological_processregulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
S0010881biological_processregulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
S0016240biological_processautophagosome membrane docking
S0019855molecular_functioncalcium channel inhibitor activity
S0019901molecular_functionprotein kinase binding
S0019904molecular_functionprotein domain specific binding
S0030017cellular_componentsarcomere
S0030235molecular_functionnitric-oxide synthase regulator activity
S0030426cellular_componentgrowth cone
S0030672cellular_componentsynaptic vesicle membrane
S0031432molecular_functiontitin binding
S0031514cellular_componentmotile cilium
S0031800molecular_functiontype 3 metabotropic glutamate receptor binding
S0031966cellular_componentmitochondrial membrane
S0032465biological_processregulation of cytokinesis
S0032991cellular_componentprotein-containing complex
S0034704cellular_componentcalcium channel complex
S0035458biological_processcellular response to interferon-beta
S0042995cellular_componentcell projection
S0043209cellular_componentmyelin sheath
S0043539molecular_functionprotein serine/threonine kinase activator activity
S0043548molecular_functionphosphatidylinositol 3-kinase binding
S0044305cellular_componentcalyx of Held
S0044325molecular_functiontransmembrane transporter binding
S0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
S0046872molecular_functionmetal ion binding
S0048306molecular_functioncalcium-dependent protein binding
S0050998molecular_functionnitric-oxide synthase binding
S0051412biological_processresponse to corticosterone
S0051592biological_processresponse to calcium ion
S0051649biological_processestablishment of localization in cell
S0055117biological_processregulation of cardiac muscle contraction
S0060314biological_processregulation of ryanodine-sensitive calcium-release channel activity
S0060315biological_processnegative regulation of ryanodine-sensitive calcium-release channel activity
S0071346biological_processcellular response to type II interferon
S0072542molecular_functionprotein phosphatase activator activity
S0090150biological_processestablishment of protein localization to membrane
S0090151biological_processestablishment of protein localization to mitochondrial membrane
S0097225cellular_componentsperm midpiece
S0097720biological_processcalcineurin-mediated signaling
S0098685cellular_componentSchaffer collateral - CA1 synapse
S0098901biological_processregulation of cardiac muscle cell action potential
S0099523cellular_componentpresynaptic cytosol
S0099524cellular_componentpostsynaptic cytosol
S0140056biological_processorganelle localization by membrane tethering
S0140238biological_processpresynaptic endocytosis
S0150034cellular_componentdistal axon
S1900242biological_processregulation of synaptic vesicle endocytosis
S1902494cellular_componentcatalytic complex
S1990456biological_processmitochondrion-endoplasmic reticulum membrane tethering
S2000300biological_processregulation of synaptic vesicle exocytosis
Functional Information from PROSITE/UniProt
site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DKDGDGTITtkEL
ChainResidueDetails
BASP20-LEU32
BASP56-PHE68
BASP93-LEU105
BASP129-PHE141

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues104
DetailsDomain: {"description":"Myosin N-terminal SH3-like","evidences":[{"source":"PROSITE-ProRule","id":"PRU01190","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues44
DetailsDomain: {"description":"IQ 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00116","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues48
DetailsDomain: {"description":"IQ 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00116","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues44
DetailsDomain: {"description":"IQ 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00116","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues48
DetailsDomain: {"description":"IQ 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00116","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues48
DetailsDomain: {"description":"IQ 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00116","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues44
DetailsRegion: {"description":"Actin-binding","evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues14
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues420
DetailsDomain: {"description":"EF-hand 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI10
Number of Residues420
DetailsDomain: {"description":"EF-hand 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI11
Number of Residues384
DetailsDomain: {"description":"EF-hand 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI12
Number of Residues864
DetailsRegion: {"description":"Necessary and sufficient for interaction with PCP4","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI13
Number of Residues240
DetailsBinding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00448","evidenceCode":"ECO:0000255"},{"source":"PDB","id":"4HEX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4ZLK","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI14
Number of Residues12
DetailsModified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI15
Number of Residues12
DetailsModified residue: {"description":"Phosphothreonine; by CaMK4","evidences":[{"source":"UniProtKB","id":"P0DP29","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI16
Number of Residues12
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI17
Number of Residues12
DetailsModified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI18
Number of Residues12
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"18034455","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI19
Number of Residues12
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

site_idSWS_FT_FI20
Number of Residues12
DetailsModified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI21
Number of Residues12
DetailsModified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI22
Number of Residues12
DetailsModified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P0DP23","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI23
Number of Residues24
DetailsCross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"UniProtKB","id":"P62157","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

Catalytic Information from CSA
site_idCSA1
Number of Residues4
DetailsAnnotated By Reference To The Literature 1vom
ChainResidueDetails
AGLY166
AGLY440
AASN214
AGLU442

site_idCSA2
Number of Residues4
DetailsAnnotated By Reference To The Literature 1vom
ChainResidueDetails
MGLY166
MGLY440
MASN214
MGLU442

239803

PDB entries from 2025-08-06

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