Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

2DB4

Crystal structure of rotor ring with DCCD of the V- ATPase from Enterococcus hirae

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005886	cellular_component	plasma membrane
A	0006814	biological_process	sodium ion transport
A	0015078	molecular_function	proton transmembrane transporter activity
A	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
A	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
A	0042802	molecular_function	identical protein binding
A	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
A	1902600	biological_process	proton transmembrane transport
B	0005886	cellular_component	plasma membrane
B	0006814	biological_process	sodium ion transport
B	0015078	molecular_function	proton transmembrane transporter activity
B	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
B	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
B	0042802	molecular_function	identical protein binding
B	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
B	1902600	biological_process	proton transmembrane transport
C	0005886	cellular_component	plasma membrane
C	0006814	biological_process	sodium ion transport
C	0015078	molecular_function	proton transmembrane transporter activity
C	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
C	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
C	0042802	molecular_function	identical protein binding
C	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
C	1902600	biological_process	proton transmembrane transport
D	0005886	cellular_component	plasma membrane
D	0006814	biological_process	sodium ion transport
D	0015078	molecular_function	proton transmembrane transporter activity
D	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
D	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
D	0042802	molecular_function	identical protein binding
D	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
D	1902600	biological_process	proton transmembrane transport
E	0005886	cellular_component	plasma membrane
E	0006814	biological_process	sodium ion transport
E	0015078	molecular_function	proton transmembrane transporter activity
E	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
E	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
E	0042802	molecular_function	identical protein binding
E	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
E	1902600	biological_process	proton transmembrane transport
F	0005886	cellular_component	plasma membrane
F	0006814	biological_process	sodium ion transport
F	0015078	molecular_function	proton transmembrane transporter activity
F	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
F	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
F	0042802	molecular_function	identical protein binding
F	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
F	1902600	biological_process	proton transmembrane transport
G	0005886	cellular_component	plasma membrane
G	0006814	biological_process	sodium ion transport
G	0015078	molecular_function	proton transmembrane transporter activity
G	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
G	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
G	0042802	molecular_function	identical protein binding
G	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0005886	cellular_component	plasma membrane
H	0006814	biological_process	sodium ion transport
H	0015078	molecular_function	proton transmembrane transporter activity
H	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
H	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
H	0042802	molecular_function	identical protein binding
H	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
H	1902600	biological_process	proton transmembrane transport
I	0005886	cellular_component	plasma membrane
I	0006814	biological_process	sodium ion transport
I	0015078	molecular_function	proton transmembrane transporter activity
I	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
I	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
I	0042802	molecular_function	identical protein binding
I	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
J	0005886	cellular_component	plasma membrane
J	0006814	biological_process	sodium ion transport
J	0015078	molecular_function	proton transmembrane transporter activity
J	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
J	0033179	cellular_component	proton-transporting V-type ATPase, V0 domain
J	0042802	molecular_function	identical protein binding
J	0046961	molecular_function	proton-transporting ATPase activity, rotational mechanism
J	1902600	biological_process	proton transmembrane transport

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW A 201

Chain	Residue
A	ALA136
A	GLU139
A	THR140
A	HOH325

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA A 202

Chain	Residue
A	GLN110
A	GLU139
A	LEU61
A	PRO62
A	GLY63
A	THR64
A	GLN65

site_id	AC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG A 203

Chain	Residue
A	LEU17
A	THR21
A	PHE105
J	PHE101
J	PHE105

site_id	AC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG A 204

Chain	Residue
A	MET1
A	MET2
A	LEU17
B	LHG204
J	LHG204

site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE UMQ A 205

Chain	Residue
A	GLN54

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE UMQ A 206

Chain	Residue
A	GLU50
A	PHE52
A	GLY53

site_id	AC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW B 201

Chain	Residue
B	ALA136
B	GLU139
B	THR140
B	HOH322

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA B 202

Chain	Residue
B	LEU61
B	PRO62
B	GLY63
B	THR64
B	GLN65
B	GLN110
B	GLU139

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LHG B 203

Chain	Residue
A	PHE105
B	LEU17
B	THR21
B	PHE105

site_id	BC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG B 204

Chain	Residue
A	LHG204
B	MET1
B	MET2
B	LEU17
C	LHG204

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW C 201

Chain	Residue
C	ALA136
C	GLU139
C	THR140
C	HOH314

site_id	BC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA C 202

Chain	Residue
C	LEU61
C	PRO62
C	GLY63
C	THR64
C	GLN65
C	GLN110
C	GLU139

site_id	BC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LHG C 203

Chain	Residue
B	PHE105
C	LEU17
C	THR21
C	PHE105

site_id	BC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG C 204

Chain	Residue
B	LHG204
C	MET1
C	MET2
C	LEU17
D	LHG203

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG C 205

Chain	Residue
C	PHE101
C	PHE105
D	LEU17
D	THR21
D	PHE105

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE UMQ C 206

Chain	Residue
C	GLN54
C	PRO125
C	THR129
F	LYS123
F	PRO125
F	GLU126

site_id	BC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW D 201

Chain	Residue
D	ALA136
D	GLU139
D	THR140
D	HOH314

site_id	BC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA D 202

Chain	Residue
D	LEU61
D	PRO62
D	GLY63
D	THR64
D	GLN65
D	GLN110
D	GLU139

site_id	CC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LHG D 203

Chain	Residue
C	MET2
C	LHG204
D	MET1
D	MET2
D	LEU17
E	LHG203

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LHG D 204

Chain	Residue
D	PHE101
D	PHE105
E	LEU17
E	THR21
E	LEU104
E	PHE105

site_id	CC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE UMQ D 205

Chain	Residue
D	GLU50
D	PHE52
D	GLY53
D	GLN54

site_id	CC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW E 201

Chain	Residue
E	ALA136
E	GLU139
E	THR140
E	HOH317

site_id	CC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA E 202

Chain	Residue
E	LEU61
E	PRO62
E	GLY63
E	THR64
E	GLN65
E	GLN110
E	GLU139

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LHG E 203

Chain	Residue
D	MET2
D	LHG203
E	MET1
E	MET2
E	LEU17
F	LHG204

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE UMQ E 204

Chain	Residue
E	GLU50
E	PHE52
E	GLY53
E	GLN54

site_id	CC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW F 201

Chain	Residue
F	ALA136
F	GLU139
F	THR140
F	HOH320

site_id	CC9
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA F 202

Chain	Residue
F	LEU61
F	PRO62
F	GLY63
F	THR64
F	GLN65
F	GLN110
F	GLU139

site_id	DC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LHG F 203

Chain	Residue
E	PHE105
F	LEU17
F	THR21
F	PHE105

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG F 204

Chain	Residue
E	LHG203
F	MET1
F	MET2
F	LEU17
G	LHG203

site_id	DC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG F 205

Chain	Residue
F	PHE101
F	PHE105
G	LEU17
G	THR21
G	PHE105

site_id	DC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE UMQ F 206

Chain	Residue
C	LYS123
C	LYS124
C	PRO125
C	GLU126
F	GLN54
F	PRO125
F	GLU126
F	THR129

site_id	DC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW G 201

Chain	Residue
G	ALA136
G	GLU139
G	THR140
G	HOH324

site_id	DC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA G 202

Chain	Residue
G	LEU61
G	PRO62
G	GLY63
G	THR64
G	GLN65
G	GLN110
G	GLU139

site_id	DC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE LHG G 203

Chain	Residue
F	MET2
F	LHG204
G	MET1
G	MET2
G	LEU17
H	LHG203

site_id	DC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LHG G 204

Chain	Residue
G	PHE101
G	PHE105
H	LEU17
H	THR21

site_id	DC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW H 201

Chain	Residue
H	ALA136
H	GLU139
H	THR140
H	HOH332

site_id	EC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA H 202

Chain	Residue
H	LEU61
H	PRO62
H	GLY63
H	THR64
H	GLN65
H	GLN110
H	GLU139

site_id	EC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG H 203

Chain	Residue
G	MET2
G	LHG203
H	MET1
H	MET2
I	LHG204

site_id	EC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE UMQ H 204

Chain	Residue
H	GLU50
H	GLY53
H	GLN54

site_id	EC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW I 201

Chain	Residue
I	ALA136
I	GLU139
I	THR140
I	HOH347

site_id	EC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA I 202

Chain	Residue
I	LEU61
I	PRO62
I	GLY63
I	THR64
I	GLN65
I	GLN110
I	GLU139

site_id	EC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LHG I 203

Chain	Residue
H	PHE105
I	LEU17
I	THR21
I	PHE105

site_id	EC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG I 204

Chain	Residue
H	LHG203
I	MET1
I	MET2
I	LEU17
J	LHG204

site_id	EC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE UMQ I 205

Chain	Residue
I	GLY53

site_id	EC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE DCW J 201

Chain	Residue
J	ALA136
J	GLU139
J	THR140
J	HOH330

site_id	FC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE NA J 202

Chain	Residue
J	LEU61
J	PRO62
J	GLY63
J	THR64
J	GLN65
J	GLN110
J	GLU139

site_id	FC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE LHG J 203

Chain	Residue
I	PHE101
I	PHE105
J	LEU17
J	THR21
J	PHE105

site_id	FC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE LHG J 204

Chain	Residue
A	LHG204
I	MET2
I	LHG204
J	MET2

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	800
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
A	GLY11-ALA31
C	LEU60-LEU80
C	GLY89-ALA109
C	ILE132-LEU152
D	GLY11-ALA31
D	LEU60-LEU80
D	GLY89-ALA109
D	ILE132-LEU152
E	GLY11-ALA31
E	LEU60-LEU80
E	GLY89-ALA109
A	LEU60-LEU80
E	ILE132-LEU152
F	GLY11-ALA31
F	LEU60-LEU80
F	GLY89-ALA109
F	ILE132-LEU152
G	GLY11-ALA31
G	LEU60-LEU80
G	GLY89-ALA109
G	ILE132-LEU152
H	GLY11-ALA31
A	GLY89-ALA109
H	LEU60-LEU80
H	GLY89-ALA109
H	ILE132-LEU152
I	GLY11-ALA31
I	LEU60-LEU80
I	GLY89-ALA109
I	ILE132-LEU152
J	GLY11-ALA31
J	LEU60-LEU80
J	GLY89-ALA109
A	ILE132-LEU152
J	ILE132-LEU152
B	GLY11-ALA31
B	LEU60-LEU80
B	GLY89-ALA109
B	ILE132-LEU152
C	GLY11-ALA31

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)