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2D2R

Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase

Functional Information from GO Data
ChainGOidnamespacecontents
A0000287molecular_functionmagnesium ion binding
A0002094molecular_functionpolyprenyltransferase activity
A0004659molecular_functionprenyltransferase activity
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
A0016094biological_processpolyprenol biosynthetic process
A0016740molecular_functiontransferase activity
A0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
A0030145molecular_functionmanganese ion binding
A0033850molecular_functionZ-farnesyl diphosphate synthase activity
A0046872molecular_functionmetal ion binding
B0000287molecular_functionmagnesium ion binding
B0002094molecular_functionpolyprenyltransferase activity
B0004659molecular_functionprenyltransferase activity
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0008834molecular_functiondi-trans,poly-cis-undecaprenyl-diphosphate synthase activity
B0016094biological_processpolyprenol biosynthetic process
B0016740molecular_functiontransferase activity
B0016765molecular_functiontransferase activity, transferring alkyl or aryl (other than methyl) groups
B0030145molecular_functionmanganese ion binding
B0033850molecular_functionZ-farnesyl diphosphate synthase activity
B0046872molecular_functionmetal ion binding
Functional Information from PROSITE/UniProt
site_idPS01066
Number of Residues18
DetailsUPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. DLLLRTGGemRlSnFLLW
ChainResidueDetails
AASP176-TRP193

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000250
ChainResidueDetails
AASP13
BASP13

site_idSWS_FT_FI2
Number of Residues2
DetailsACT_SITE: Proton acceptor => ECO:0000250
ChainResidueDetails
AASN61
BASN61

site_idSWS_FT_FI3
Number of Residues20
DetailsBINDING: BINDING => ECO:0000250
ChainResidueDetails
AASP13
AGLU199
BASP13
BGLY14
BTRP18
BHIS30
BSER58
BTRP62
BARG64
BARG180
BARG186
AGLY14
BGLU199
ATRP18
AHIS30
ASER58
ATRP62
AARG64
AARG180
AARG186

site_idSWS_FT_FI4
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|Ref.3
ChainResidueDetails
AARG26
BARG26

218853

PDB entries from 2024-04-24

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