2D0V
Crystal structure of methanol dehydrogenase from Hyphomicrobium denitrificans
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0016020 | cellular_component | membrane |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| B | 0015945 | biological_process | methanol metabolic process |
| B | 0015946 | biological_process | methanol oxidation |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| D | 0005509 | molecular_function | calcium ion binding |
| D | 0016020 | cellular_component | membrane |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| D | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| D | 0046872 | molecular_function | metal ion binding |
| E | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| E | 0015945 | biological_process | methanol metabolic process |
| E | 0015946 | biological_process | methanol oxidation |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
| I | 0005509 | molecular_function | calcium ion binding |
| I | 0016020 | cellular_component | membrane |
| I | 0016491 | molecular_function | oxidoreductase activity |
| I | 0016614 | molecular_function | oxidoreductase activity, acting on CH-OH group of donors |
| I | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| I | 0046872 | molecular_function | metal ion binding |
| J | 0004022 | molecular_function | alcohol dehydrogenase (NAD+) activity |
| J | 0015945 | biological_process | methanol metabolic process |
| J | 0015946 | biological_process | methanol oxidation |
| J | 0016491 | molecular_function | oxidoreductase activity |
| J | 0052933 | molecular_function | alcohol dehydrogenase (cytochrome c(L)) activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA A 775 |
| Chain | Residue |
| A | GLU177 |
| A | ASN261 |
| A | ASP303 |
| A | PQQ601 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CA D 775 |
| Chain | Residue |
| D | GLU177 |
| D | ASN261 |
| D | ASP303 |
| D | PQQ601 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA I 775 |
| Chain | Residue |
| I | ASN261 |
| I | PQQ601 |
| I | GLU177 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PQQ A 601 |
| Chain | Residue |
| A | GLU55 |
| A | ARG109 |
| A | THR159 |
| A | SER174 |
| A | GLY175 |
| A | ALA176 |
| A | GLU177 |
| A | THR241 |
| A | TRP243 |
| A | ASP303 |
| A | ARG331 |
| A | ASN394 |
| A | GLN395 |
| A | TRP476 |
| A | GLY539 |
| A | TRP540 |
| A | PRO541 |
| A | CA775 |
| A | HOH810 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE PQQ D 601 |
| Chain | Residue |
| D | GLU55 |
| D | ARG109 |
| D | THR159 |
| D | SER174 |
| D | GLY175 |
| D | ALA176 |
| D | GLU177 |
| D | THR241 |
| D | TRP243 |
| D | ASN261 |
| D | ASP303 |
| D | ARG331 |
| D | ASN394 |
| D | GLN395 |
| D | TRP476 |
| D | GLY539 |
| D | TRP540 |
| D | PRO541 |
| D | CA775 |
| D | HOH788 |
| site_id | AC6 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE PQQ I 601 |
| Chain | Residue |
| I | GLU55 |
| I | CYS104 |
| I | ARG109 |
| I | THR159 |
| I | SER174 |
| I | GLY175 |
| I | ALA176 |
| I | GLU177 |
| I | THR241 |
| I | TRP243 |
| I | ASP303 |
| I | ARG331 |
| I | ASN394 |
| I | GLN395 |
| I | TRP476 |
| I | GLY539 |
| I | TRP540 |
| I | CA775 |
| I | HOH926 |
Functional Information from PROSITE/UniProt
| site_id | PS00363 |
| Number of Residues | 29 |
| Details | BACTERIAL_PQQ_1 Bacterial quinoprotein dehydrogenases signature 1. NWvmpGKnydsnnYStstqINvdNVkqLK |
| Chain | Residue | Details |
| A | ASN13-LYS41 |
| site_id | PS00364 |
| Number of Residues | 22 |
| Details | BACTERIAL_PQQ_2 Bacterial quinoprotein dehydrogenases signature 2. WgwyaYDpaaNLIYYgsGnpAP |
| Chain | Residue | Details |
| A | TRP243-PRO264 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g72 |
| Chain | Residue | Details |
| A | ASP303 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g72 |
| Chain | Residue | Details |
| D | ASP303 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1g72 |
| Chain | Residue | Details |
| I | ASP303 |
