2D0I

Crystal Structure PH0520 protein from Pyrococcus horikoshii OT3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
A	0030267	molecular_function	glyoxylate reductase (NADPH) activity
A	0051287	molecular_function	NAD binding
B	0005829	cellular_component	cytosol
B	0016491	molecular_function	oxidoreductase activity
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
B	0030267	molecular_function	glyoxylate reductase (NADPH) activity
B	0051287	molecular_function	NAD binding
C	0005829	cellular_component	cytosol
C	0016491	molecular_function	oxidoreductase activity
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
C	0030267	molecular_function	glyoxylate reductase (NADPH) activity
C	0051287	molecular_function	NAD binding
D	0005829	cellular_component	cytosol
D	0016491	molecular_function	oxidoreductase activity
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
D	0030267	molecular_function	glyoxylate reductase (NADPH) activity
D	0051287	molecular_function	NAD binding

Functional Information from PROSITE/UniProt

site_id	PS00065
Number of Residues	28
Details	D_2_HYDROXYACID_DH_1 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. VGILGmGAIGkaiarrlipfgvk.LYyWS

Chain	Residue	Details
A	VAL149-SER176

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
A	GLU265
A	HIS284

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
B	GLU265
B	HIS284

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
C	GLU265
C	HIS284

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site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
D	GLU265
D	HIS284

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