Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
A | 0005829 | cellular_component | cytosol |
A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
A | 0016831 | molecular_function | carboxy-lyase activity |
A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
B | 0005829 | cellular_component | cytosol |
B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
B | 0016831 | molecular_function | carboxy-lyase activity |
B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE U5P A 401 |
Chain | Residue |
A | ASP7 |
A | GLN167 |
A | GLY185 |
A | ARG186 |
A | HOH602 |
A | HOH603 |
A | HOH606 |
A | HOH615 |
B | ASP62 |
B | ILE63 |
B | THR66 |
A | LYS29 |
A | ASN31 |
A | ASP57 |
A | LYS59 |
A | MET108 |
A | SER109 |
A | PRO162 |
A | ILE164 |
site_id | AC2 |
Number of Residues | 18 |
Details | BINDING SITE FOR RESIDUE U5P B 402 |
Chain | Residue |
A | ASP62 |
A | ILE63 |
A | THR66 |
B | ASP7 |
B | LYS29 |
B | ASN31 |
B | ASP57 |
B | LYS59 |
B | MET108 |
B | SER109 |
B | PRO162 |
B | GLN167 |
B | GLY185 |
B | ARG186 |
B | HOH412 |
B | HOH414 |
B | HOH415 |
B | HOH420 |
site_id | AC3 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE CIT A 501 |
Chain | Residue |
A | ARG68 |
A | LEU69 |
A | ARG72 |
A | HOH656 |
A | HOH663 |
A | HOH700 |
A | HOH711 |
B | ARG68 |
B | LEU69 |
B | ARG72 |
site_id | AC4 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE GOL A 601 |
Chain | Residue |
A | GLU98 |
A | LEU99 |
A | ARG186 |
A | ALA187 |
A | ALA191 |
A | HOH658 |
A | HOH684 |
Functional Information from PROSITE/UniProt
site_id | PS00156 |
Number of Residues | 14 |
Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. IIaDlKlaDIPnTN |
Chain | Residue | Details |
A | ILE54-ASN67 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
A | LYS59 | |
B | LYS59 | |
site_id | SWS_FT_FI2 |
Number of Residues | 14 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP7 | |
B | ASP57 | |
B | SER109 | |
B | PRO162 | |
B | GLY185 | |
B | ARG186 | |
A | LYS29 | |
A | ASP57 | |
A | SER109 | |
A | PRO162 | |
A | GLY185 | |
A | ARG186 | |
B | ASP7 | |
B | LYS29 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
A | ASP57 | |
A | LYS59 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
B | ASP57 | |
B | LYS59 | |
site_id | CSA3 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
A | ASP62 | |
A | LYS59 | |
A | ASP57 | |
A | LYS29 | |
site_id | CSA4 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1dbt |
Chain | Residue | Details |
B | ASP62 | |
B | LYS59 | |
B | ASP57 | |
B | LYS29 | |