2CYY

Crystal structure of PH1519 from Pyrococcus horikosii OT3

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0005515	molecular_function	protein binding
A	0005829	cellular_component	cytosol
A	0006351	biological_process	DNA-templated transcription
A	0042802	molecular_function	identical protein binding
A	0043200	biological_process	response to amino acid
A	0043565	molecular_function	sequence-specific DNA binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CA A 2001

Chain	Residue
A	THR146
A	HOH2007
A	HOH2046

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A 2002

Chain	Residue
A	GLY64
A	SER66
A	LYS112
A	HOH2018
A	HOH2098
A	HOH2138

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 2003

Chain	Residue
A	SER66
A	SER66
A	HOH2029
A	HOH2029

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CA A 2004

Chain	Residue
A	HOH2054
A	HOH2140
A	HOH2217
A	HOH2218

---

site_id	AC5
Number of Residues	11
Details	BINDING SITE FOR RESIDUE GLN A 1001

Chain	Residue
A	GLU61
A	SER66
A	LEU68
A	ARG110
A	SER114
A	VAL138
A	LEU139
A	THR141
A	HOH2020
A	HOH2024
A	HOH2213

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	61
Details	Domain: {"description":"HTH asnC-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00319","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	19
Details	DNA binding: {"description":"H-T-H motif","evidences":[{"source":"PROSITE-ProRule","id":"PRU00319","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19004003","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZNY","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"19004003","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2ZNZ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---