2CUN
Crystal structure of Phosphoglycerate Kinase from Pyrococcus horikoshii OT3
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004618 | molecular_function | phosphoglycerate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006094 | biological_process | gluconeogenesis |
| A | 0006096 | biological_process | glycolytic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0043531 | molecular_function | ADP binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004618 | molecular_function | phosphoglycerate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006094 | biological_process | gluconeogenesis |
| B | 0006096 | biological_process | glycolytic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0043531 | molecular_function | ADP binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 505 |
| Chain | Residue |
| A | ARG114 |
| A | ARG154 |
| A | GOL501 |
| A | HOH591 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 506 |
| Chain | Residue |
| B | ARG114 |
| B | ARG154 |
| B | GOL502 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 3PG A 503 |
| Chain | Residue |
| A | GLY358 |
| A | GLY359 |
| A | HIS360 |
| A | GLY380 |
| A | GLY381 |
| A | GOL501 |
| A | HOH515 |
| A | HOH620 |
| A | ARG34 |
| A | LYS200 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 3PG B 504 |
| Chain | Residue |
| B | ARG34 |
| B | LYS200 |
| B | GLY358 |
| B | GLY359 |
| B | HIS360 |
| B | GLY380 |
| B | GLY381 |
| B | GOL502 |
| B | HOH509 |
| B | HOH551 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 501 |
| Chain | Residue |
| A | ASP19 |
| A | ASN21 |
| A | ARG34 |
| A | HIS57 |
| A | ARG114 |
| A | ALA150 |
| A | 3PG503 |
| A | CL505 |
| site_id | AC6 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE GOL B 502 |
| Chain | Residue |
| B | ASP19 |
| B | ASN21 |
| B | ARG34 |
| B | HIS57 |
| B | ALA150 |
| B | HIS153 |
| B | ARG154 |
| B | 3PG504 |
| B | CL506 |
| B | HOH575 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD B 507 |
| Chain | Residue |
| B | ALA33 |
| B | ARG34 |
| B | GLY359 |
| B | ILE362 |
| B | SER377 |
| B | THR378 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE MPD A 508 |
| Chain | Residue |
| A | ARG34 |
| A | GLY359 |
| A | SER377 |
| A | THR378 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MPD A 509 |
| Chain | Residue |
| A | ASP89 |
| A | ILE90 |
| A | PHE91 |
| A | GLY92 |
| A | HOH542 |
| B | PHE115 |
Functional Information from PROSITE/UniProt
| site_id | PS00111 |
| Number of Residues | 11 |
| Details | PGLYCERATE_KINASE Phosphoglycerate kinase signature. TVFLRvDlNSP |
| Chain | Residue | Details |
| A | THR13-PRO23 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 22 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"JUN-2005","submissionDatabase":"PDB data bank","title":"Crystal structure of phosphoglycerate kinase from Pyrococcus horikoshii OT3.","authoringGroup":["RIKEN structural genomics initiative (RSGI)"]}}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 13pk |
| Chain | Residue | Details |
| A | ARG34 | |
| A | GLY359 | |
| A | GLY381 | |
| A | LYS200 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 13pk |
| Chain | Residue | Details |
| B | ARG34 | |
| B | GLY359 | |
| B | GLY381 | |
| B | LYS200 |
