2CUK

Crystal structure of TT0316 protein from Thermus thermophilus HB8

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005829	cellular_component	cytosol
A	0016491	molecular_function	oxidoreductase activity
A	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
A	0030267	molecular_function	glyoxylate reductase (NADPH) activity
A	0051287	molecular_function	NAD binding
B	0005829	cellular_component	cytosol
B	0016491	molecular_function	oxidoreductase activity
B	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
B	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
B	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
B	0030267	molecular_function	glyoxylate reductase (NADPH) activity
B	0051287	molecular_function	NAD binding
C	0005829	cellular_component	cytosol
C	0016491	molecular_function	oxidoreductase activity
C	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
C	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
C	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
C	0030267	molecular_function	glyoxylate reductase (NADPH) activity
C	0051287	molecular_function	NAD binding
D	0005829	cellular_component	cytosol
D	0016491	molecular_function	oxidoreductase activity
D	0016614	molecular_function	oxidoreductase activity, acting on CH-OH group of donors
D	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
D	0016618	molecular_function	hydroxypyruvate reductase [NAD(P)H] activity
D	0030267	molecular_function	glyoxylate reductase (NADPH) activity
D	0051287	molecular_function	NAD binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE NHE C 1401

Chain	Residue
C	GLY153
C	ARG154
C	ILE155
C	ALA229
C	ARG230
C	HOH1453
C	HOH1486
C	HOH1560

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Functional Information from PROSITE/UniProt

site_id	PS00670
Number of Residues	23
Details	D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. LLkeADVVsLHtPltpeThrLlN

Chain	Residue	Details
A	LEU190-ASN212

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site_id	PS00671
Number of Residues	17
Details	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MKrGaILLNtARGaLVD

Chain	Residue	Details
A	MET219-ASP235

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
A	HIS277
A	GLU258

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
B	HIS277
B	GLU258

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site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
C	HIS277
C	GLU258

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site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1psd

Chain	Residue	Details
D	HIS277
D	GLU258

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