2CS8

Solution structure of tandem repeat of the fifth and sixth zinc-finger C2HC domains from human ST18

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0006355	biological_process	regulation of DNA-templated transcription
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	CYS12
A	CYS17
A	HIS30
A	CYS36

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 601

Chain	Residue
A	CYS65
A	CYS70
A	HIS83
A	CYS89

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	43
Details	ZN_FING: CCHHC-type 6 => ECO:0000255|PROSITE-ProRule:PRU01143

Chain	Residue	Details
A	LYS56-GLY99

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site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01143

Chain	Residue	Details
A	CYS12
A	CYS17
A	HIS30
A	CYS36
A	CYS65
A	CYS70
A	HIS83
A	CYS89

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