Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006164 | biological_process | purine nucleotide biosynthetic process |
| A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
| A | 0009152 | biological_process | purine ribonucleotide biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A1311 |
| Chain | Residue |
| A | TYR42 |
| A | GLN261 |
| A | ARG264 |
| A | HOH2342 |
| A | HOH2410 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A1312 |
| Chain | Residue |
| A | HOH2333 |
| A | HOH2411 |
| A | HOH2412 |
| A | ARG289 |
| A | TRP304 |
| A | SER305 |
| A | HOH2332 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ASP A1309 |
| Chain | Residue |
| A | ARG73 |
| A | LEU76 |
| A | ASP78 |
| A | HIS110 |
| A | HOH2406 |
| A | HOH2407 |
| A | HOH2408 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ASP A1310 |
| Chain | Residue |
| A | VAL183 |
| A | GLY184 |
| A | GLU185 |
| A | ASP186 |
| A | LEU187 |
| A | HOH2409 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE SSS A1308 |
| Chain | Residue |
| A | LYS19 |
| A | SER40 |
| A | ALA41 |
| A | TYR42 |
| A | ASP43 |
| A | ILE120 |
| A | ARG122 |
| A | GLY127 |
| A | SER128 |
| A | ASP215 |
| A | THR216 |
| A | ASP239 |
| A | ARG242 |
| A | ARG264 |
| A | HOH2265 |
| A | HOH2324 |
| A | HOH2326 |
| A | HOH2404 |
| A | HOH2405 |
Functional Information from PROSITE/UniProt
| site_id | PS01057 |
| Number of Residues | 15 |
| Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. LIPLEvIVRgyiTGS |
| Chain | Residue | Details |
| A | LEU114-SER128 | |
| site_id | PS01058 |
| Number of Residues | 9 |
| Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. IADtKFEFG |
| Chain | Residue | Details |
| A | ILE213-GLY221 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"N-acetylserine","evidences":[{"source":"PubMed","id":"9551557","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22814378","evidenceCode":"ECO:0007744"}]} |
