Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004639 | molecular_function | phosphoribosylaminoimidazolesuccinocarboxamide synthase activity |
A | 0005515 | molecular_function | protein binding |
A | 0005524 | molecular_function | ATP binding |
A | 0005634 | cellular_component | nucleus |
A | 0005737 | cellular_component | cytoplasm |
A | 0006164 | biological_process | purine nucleotide biosynthetic process |
A | 0006189 | biological_process | 'de novo' IMP biosynthetic process |
A | 0016874 | molecular_function | ligase activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | BINDING SITE FOR RESIDUE SO4 A1311 |
Chain | Residue |
A | TYR42 |
A | GLN261 |
A | ARG264 |
A | HOH2342 |
A | HOH2410 |
site_id | AC2 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE SO4 A1312 |
Chain | Residue |
A | HOH2333 |
A | HOH2411 |
A | HOH2412 |
A | ARG289 |
A | TRP304 |
A | SER305 |
A | HOH2332 |
site_id | AC3 |
Number of Residues | 7 |
Details | BINDING SITE FOR RESIDUE ASP A1309 |
Chain | Residue |
A | ARG73 |
A | LEU76 |
A | ASP78 |
A | HIS110 |
A | HOH2406 |
A | HOH2407 |
A | HOH2408 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE ASP A1310 |
Chain | Residue |
A | VAL183 |
A | GLY184 |
A | GLU185 |
A | ASP186 |
A | LEU187 |
A | HOH2409 |
site_id | AC5 |
Number of Residues | 19 |
Details | BINDING SITE FOR RESIDUE SSS A1308 |
Chain | Residue |
A | LYS19 |
A | SER40 |
A | ALA41 |
A | TYR42 |
A | ASP43 |
A | ILE120 |
A | ARG122 |
A | GLY127 |
A | SER128 |
A | ASP215 |
A | THR216 |
A | ASP239 |
A | ARG242 |
A | ARG264 |
A | HOH2265 |
A | HOH2324 |
A | HOH2326 |
A | HOH2404 |
A | HOH2405 |
Functional Information from PROSITE/UniProt
site_id | PS01057 |
Number of Residues | 15 |
Details | SAICAR_SYNTHETASE_1 SAICAR synthetase signature 1. LIPLEvIVRgyiTGS |
Chain | Residue | Details |
A | LEU114-SER128 | |
site_id | PS01058 |
Number of Residues | 9 |
Details | SAICAR_SYNTHETASE_2 SAICAR synthetase signature 2. IADtKFEFG |
Chain | Residue | Details |
A | ILE213-GLY221 | |
Functional Information from SwissProt/UniProt