Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004674 | molecular_function | protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1324 |
| Chain | Residue |
| A | PRO272 |
| A | ILE273 |
| A | GLU274 |
| A | ARG288 |
| A | HOH2253 |
| A | HOH2254 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1325 |
| Chain | Residue |
| A | ARG260 |
| A | HOH2255 |
| A | HOH2256 |
| A | ARG214 |
| A | GLN250 |
| A | GLY251 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1326 |
| Chain | Residue |
| A | LYS110 |
| A | SER135 |
| A | LEU136 |
| A | HOH2257 |
| A | HOH2258 |
| A | HOH2259 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1327 |
| Chain | Residue |
| A | ARG161 |
| A | LYS190 |
| A | LYS207 |
| A | GLU225 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1328 |
| Chain | Residue |
| A | ARG228 |
| A | LYS298 |
| A | HOH2260 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE DKI A 1323 |
| Chain | Residue |
| A | ILE49 |
| A | PHE54 |
| A | LEU57 |
| A | ALA70 |
| A | GLU117 |
| A | LEU118 |
| A | LEU119 |
| A | GLY120 |
| A | GLU166 |
| A | ASN167 |
| A | LEU169 |
| A | ILE184 |
| A | ASP185 |
| A | PRO331 |
| A | THR332 |
| A | PRO333 |
| A | HOH2252 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 24 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGCGNFGELRlGknlytney..........VAIK |
| Chain | Residue | Details |
| A | ILE49-LYS72 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. LiYrDVKpeNFLI |
| Chain | Residue | Details |
| A | LEU158-ILE170 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 270 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | GLU155 | |
| A | ASP151 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASP151 | |
| A | LYS153 | |
| site_id | CSA3 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | THR201 | |
| A | ASP151 | |
| A | LYS153 | |
| site_id | CSA4 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1ir3 |
| Chain | Residue | Details |
| A | ASN156 | |
| A | ASP151 | |
| A | LYS153 | |
