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2CH9

Crystal structure of dimeric human cystatin F

Functional Information from GO Data
ChainGOidnamespacecontents
A0002020molecular_functionprotease binding
A0002577biological_processregulation of antigen processing and presentation
A0004866molecular_functionendopeptidase inhibitor activity
A0004869molecular_functioncysteine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0005764cellular_componentlysosome
A0005768cellular_componentendosome
A0005770cellular_componentlate endosome
A0005771cellular_componentmultivesicular body
A0005783cellular_componentendoplasmic reticulum
A0005794cellular_componentGolgi apparatus
A0006955biological_processimmune response
A0030414molecular_functionpeptidase inhibitor activity
A0031410cellular_componentcytoplasmic vesicle
A0031643biological_processpositive regulation of myelination
A0042803molecular_functionprotein homodimerization activity
A1903979biological_processnegative regulation of microglial cell activation
A1905146biological_processlysosomal protein catabolic process
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsMotif: {"description":"Secondary area of contact"}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues1
DetailsSite: {"description":"Reactive site"}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16601115","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

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PDB entries from 2026-02-25

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