2CFU

Crystal structure of SdsA1, an alkylsulfatase from Pseudomonas aeruginosa, in complex with 1-decane-sulfonic-acid.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0018741	molecular_function	linear primary-alkylsulfatase activity
A	0018909	biological_process	dodecyl sulfate metabolic process
A	0046983	molecular_function	protein dimerization activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 1001

Chain	Residue
A	ASP173
A	HIS174
A	GLU299
A	HIS344
A	ZN1002
A	HOH3001

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ZN A 1002

Chain	Residue
A	GLU299
A	ZN1001
A	HOH3001
A	HIS169
A	HIS171
A	GLU280

---

site_id	AC3
Number of Residues	18
Details	BINDING SITE FOR RESIDUE 1DB A 1655

Chain	Residue
A	HIS171
A	ALA172
A	ASP173
A	TYR223
A	LEU243
A	GLU280
A	HIS306
A	ASN307
A	THR310
A	ARG312
A	ARG317
A	HIS405
A	IPA1664
A	HOH2060
A	HOH2259
A	HOH2530
A	HOH2531
A	HOH2532

---

site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG A 1656

Chain	Residue
A	MET216
A	IPA1664

---

site_id	AC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PEG A 1657

Chain	Residue
A	ARG441
A	GLY463
A	GLU464
A	TYR465
A	ARG466
A	TRP467
A	HOH2533

---

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG A 1658

Chain	Residue
A	LEU609
A	LEU633
A	PHE637
A	PEG1660

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE PEG A 1659

Chain	Residue
A	ARG179
A	LEU250
A	LEU251
A	ALA536
A	HOH2534
A	HOH2535

---

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE PEG A 1660

Chain	Residue
A	LEU633
A	PEG1658

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE PEG A 1661

Chain	Residue
A	ALA39

---

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG A 1662

Chain	Residue
A	GLU159
A	ARG486
A	ARG517
A	HIS518

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PEG A 1663

Chain	Residue
A	HIS331
A	ARG335
A	SER591
A	GLU592

---

site_id	BC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE IPA A 1664

Chain	Residue
A	MET216
A	TYR223
A	ARG312
A	1DB1655
A	PEG1656
A	HOH2536

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16684886","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2015","firstPage":"1551","lastPage":"1551","volume":"48","journal":"J. Appl. Crystallogr.","title":"Sdsa polymorph isolation and improvement of their crystal quality using nonconventional crystallization techniques.","authors":["De La Mora E.","Flores-Hernandez E.","Jakoncic J.","Stojanoff V.","Siliqi D.","Sanchez-Puig N.","Moreno A."],"citationCrossReferences":[{"database":"DOI","id":"10.1107/S1600576715016556"}]}},{"source":"PDB","id":"2CFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5A23","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AIJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16684886","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"journal article","publicationDate":"2015","firstPage":"1551","lastPage":"1551","volume":"48","journal":"J. Appl. Crystallogr.","title":"Sdsa polymorph isolation and improvement of their crystal quality using nonconventional crystallization techniques.","authors":["De La Mora E.","Flores-Hernandez E.","Jakoncic J.","Stojanoff V.","Siliqi D.","Sanchez-Puig N.","Moreno A."],"citationCrossReferences":[{"database":"DOI","id":"10.1107/S1600576715016556"}]}},{"source":"PDB","id":"2CFU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CFZ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CG2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5A23","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AIJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5AJL","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16684886","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2CG2","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 2bmi

Chain	Residue	Details
A	ASP173
A	ASN307

---