2CA8

Structure of Sh28GST in complex with GSH at pH 6.0

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004364	molecular_function	glutathione transferase activity
A	0006749	biological_process	glutathione metabolic process
A	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	BINDING SITE FOR RESIDUE GSH A 1212

Chain	Residue
A	TYR10
A	SER71
A	ASP104
A	HOH2050
A	PHE11
A	ARG16
A	TRP41
A	LYS45
A	ARG52
A	LEU53
A	PRO54
A	GLU70

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PG4 A 1213

Chain	Residue
A	LYS80
A	LYS80
A	GLY86
A	GLY87
A	THR88
A	TYR92
A	TYR92

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	82
Details	Domain: {"description":"GST N-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	123
Details	Domain: {"description":"GST C-terminal"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CAQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	5
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OE8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CAQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2F8F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2F8F","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1oe8

Chain	Residue	Details
A	TYR10

---