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2CA6

MIRAS structure determination from hemihedrally twinned crystals

Functional Information from GO Data
ChainGOidnamespacecontents
A0005096molecular_functionGTPase activator activity
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0006611biological_processprotein export from nucleus
A0006913biological_processnucleocytoplasmic transport
A0031267molecular_functionsmall GTPase binding
A0034399cellular_componentnuclear periphery
A0048471cellular_componentperinuclear region of cytoplasm
B0005096molecular_functionGTPase activator activity
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006611biological_processprotein export from nucleus
B0006913biological_processnucleocytoplasmic transport
B0031267molecular_functionsmall GTPase binding
B0034399cellular_componentnuclear periphery
B0048471cellular_componentperinuclear region of cytoplasm
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE SO4 B1345
ChainResidue
AARG162
BLYS219
BHOH2120

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B1346
ChainResidue
BARG162
BHOH2062
BHOH2121
BHOH2122

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 B1347
ChainResidue
BLEU85
BHOH2017
BHOH2124
BARG50
BARG84

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B1348
ChainResidue
ALYS35
BTYR128
BLYS193
BHOH2125

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Critical residue for GTP hydrolysis
ChainResidueDetails
AARG74
BARG74

218853

PDB entries from 2024-04-24

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