2C9Z

Structure and activity of a flavonoid 3-0 glucosyltransferase reveals the basis for plant natural product modification

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008194	molecular_function	UDP-glycosyltransferase activity
A	0009718	biological_process	anthocyanin-containing compound biosynthetic process
A	0016757	molecular_function	glycosyltransferase activity
A	0033303	biological_process	quercetin O-glucoside biosynthetic process
A	0033485	biological_process	cyanidin 3-O-glucoside biosynthetic process
A	0047213	molecular_function	anthocyanidin 3-O-glucosyltransferase activity
A	0047893	molecular_function	flavonol 3-O-glucosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	BINDING SITE FOR RESIDUE UDP A1457

Chain	Residue
A	SER18
A	HIS350
A	GLY352
A	TRP353
A	ASN354
A	SER355
A	GLU358
A	HOH2220
A	HOH2221
A	HOH2223
A	THR19
A	SER277
A	GLY279
A	THR280
A	SER306
A	TRP332
A	ALA333
A	GLN335

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site_id	AC2
Number of Residues	11
Details	BINDING SITE FOR RESIDUE QUE A1458

Chain	Residue
A	SER18
A	HIS20
A	GLN84
A	PHE121
A	SER146
A	HIS150
A	GLN188
A	PHE200
A	LEU204
A	HOH2224
A	HOH2225

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Functional Information from PROSITE/UniProt

site_id	PS00375
Number of Residues	44
Details	UDPGT UDP-glycosyltransferases signature. WapQaeVLaheavgAFVTHCGwnSlweSVaggv.PLicrPffgDQ

Chain	Residue	Details
A	TRP332-GLN375

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:A0A0A1HA03

Chain	Residue	Details
A	HIS20

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Charge relay => ECO:0000250|UniProtKB:A0A0A1HA03

Chain	Residue	Details
A	ASP119

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site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:16482224, ECO:0007744|PDB:2C9Z

Chain	Residue	Details
A	SER18
A	GLN84
A	HIS150
A	GLN188
A	GLY373

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site_id	SWS_FT_FI4
Number of Residues	13
Details	BINDING: BINDING => ECO:0000305|PubMed:16482224, ECO:0007744|PDB:2C1Z

Chain	Residue	Details
A	THR19
A	SER355
A	GLU358
A	ASP374
A	GLN375
A	THR141
A	THR280
A	SER306
A	TRP332
A	ALA333
A	HIS350
A	TRP353
A	ASN354

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:16482224, ECO:0007744|PDB:2C1Z

Chain	Residue	Details
A	HIS20

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