2C8U
Structure of R21Q mutant of Sh28GST
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1206 |
| Chain | Residue |
| A | ASN12 |
| A | GLY15 |
| A | ARG16 |
| A | BME1209 |
| A | HOH2108 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1207 |
| Chain | Residue |
| A | ARG16 |
| A | ARG52 |
| A | HOH2109 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1206 |
| Chain | Residue |
| B | ASN12 |
| B | GLY15 |
| B | ARG16 |
| B | HOH2107 |
| B | HOH2112 |
| B | PHE11 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1207 |
| Chain | Residue |
| B | ARG16 |
| B | ARG52 |
| B | LEU53 |
| B | HOH2108 |
| B | HOH2109 |
| B | HOH2110 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1208 |
| Chain | Residue |
| B | PHE11 |
| B | MET114 |
| B | HOH2111 |
| B | HOH2112 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BME A 1208 |
| Chain | Residue |
| A | ARG76 |
| A | HOH2060 |
| B | ARG76 |
| B | GLU103 |
| B | HOH2051 |
| B | HOH2066 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE BME A 1209 |
| Chain | Residue |
| A | TYR110 |
| A | SO41206 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 164 |
| Details | Domain: {"description":"GST N-terminal"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CAQ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1OE8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CA8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2CAQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2F8F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12939136","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16777141","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1OE7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2C80","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2F8F","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | TYR10 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | TYR10 |
