2C80
Structure of Sh28GST in complex with S-hexyl Glutathione
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004364 | molecular_function | glutathione transferase activity |
| A | 0006749 | biological_process | glutathione metabolic process |
| A | 0016740 | molecular_function | transferase activity |
| B | 0004364 | molecular_function | glutathione transferase activity |
| B | 0006749 | biological_process | glutathione metabolic process |
| B | 0016740 | molecular_function | transferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE GTX A 1212 |
| Chain | Residue |
| A | TYR10 |
| A | TYR110 |
| A | HOH2106 |
| A | HOH2107 |
| B | ASP104 |
| B | HOH2059 |
| A | ARG16 |
| A | TRP41 |
| A | LYS45 |
| A | ARG52 |
| A | LEU53 |
| A | PRO54 |
| A | GLU70 |
| A | SER71 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE PG4 B 1212 |
| Chain | Residue |
| A | LYS80 |
| A | GLY86 |
| A | TYR92 |
| B | LYS80 |
| B | GLY86 |
| B | THR88 |
| B | TYR92 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE GTX B 1213 |
| Chain | Residue |
| A | ASP104 |
| B | TYR10 |
| B | GLY15 |
| B | ARG16 |
| B | TRP41 |
| B | LYS45 |
| B | ARG52 |
| B | LEU53 |
| B | PRO54 |
| B | GLU70 |
| B | SER71 |
| B | TYR110 |
| B | LEU113 |
| B | PHE211 |
| B | HOH2118 |
| B | HOH2119 |
| B | HOH2120 |
| B | HOH2121 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12939136, ECO:0000269|PubMed:16777141, ECO:0007744|PDB:1OE7, ECO:0007744|PDB:2C80, ECO:0007744|PDB:2CA8 |
| Chain | Residue | Details |
| A | TYR10 | |
| B | TYR10 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12939136, ECO:0000269|PubMed:16777141, ECO:0007744|PDB:1OE7, ECO:0007744|PDB:2C80, ECO:0007744|PDB:2CA8, ECO:0007744|PDB:2CAQ |
| Chain | Residue | Details |
| A | ARG16 | |
| B | ARG16 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 10 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12939136, ECO:0000269|PubMed:16777141, ECO:0007744|PDB:1OE7, ECO:0007744|PDB:1OE8, ECO:0007744|PDB:2C80, ECO:0007744|PDB:2CA8, ECO:0007744|PDB:2CAQ, ECO:0007744|PDB:2F8F |
| Chain | Residue | Details |
| A | TRP41 | |
| B | SER71 | |
| A | LYS45 | |
| A | LEU53 | |
| A | GLU70 | |
| A | SER71 | |
| B | TRP41 | |
| B | LYS45 | |
| B | LEU53 | |
| B | GLU70 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:12939136, ECO:0000269|PubMed:16777141, ECO:0007744|PDB:1OE7, ECO:0007744|PDB:2C80, ECO:0007744|PDB:2F8F |
| Chain | Residue | Details |
| A | ASP104 | |
| B | ASP104 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| A | TYR10 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1oe8 |
| Chain | Residue | Details |
| B | TYR10 |
