2C4U

Crystal structure of the apo form of the 5'-Fluoro-5'-deoxyadenosine synthase enzyme from Streptomyces cattleya

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0033846	molecular_function	adenosyl-fluoride synthase activity
B	0016740	molecular_function	transferase activity
B	0033846	molecular_function	adenosyl-fluoride synthase activity
C	0016740	molecular_function	transferase activity
C	0033846	molecular_function	adenosyl-fluoride synthase activity
D	0016740	molecular_function	transferase activity
D	0033846	molecular_function	adenosyl-fluoride synthase activity
E	0016740	molecular_function	transferase activity
E	0033846	molecular_function	adenosyl-fluoride synthase activity
F	0016740	molecular_function	transferase activity
F	0033846	molecular_function	adenosyl-fluoride synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A1299

Chain	Residue
A	TRP50
A	TYR77
A	PRO78
A	HOH2082
B	PHE254
B	ALA279
B	HOH2072

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A1300

Chain	Residue
A	ASP42
A	HOH2083
A	HOH2084
B	ASP42
B	VAL43
A	THR19
A	LYS28

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A1301

Chain	Residue
A	PHE213
A	ASN215
A	PHE254
A	ARG277
A	ALA279
A	HOH2085
C	TRP50
C	PRO78

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B1299

Chain	Residue
B	THR19
B	LYS28
B	ASP42
B	HOH2086
B	HOH2087
B	HOH2088
C	ASP42
C	VAL43

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C1299

Chain	Residue
A	ASP42
A	HOH2015
C	THR19
C	LYS28
C	ASP42
C	HOH2061

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C1300

Chain	Residue
B	TRP50
B	TYR77
B	PRO78
C	PHE213
C	ASN215
C	PHE254
C	ALA279

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D1299

Chain	Residue
D	LYS28
D	ASP42
E	ASP42
E	VAL43
F	GOL1299

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D1300

Chain	Residue
D	ASP16
D	TYR77
D	THR80
D	PHE156
D	TYR157
D	SER158
E	PHE213

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E1299

Chain	Residue
E	THR19
E	LYS28
E	ASP42
E	HOH2004
F	ASP42
F	GOL1299

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL F1299

Chain	Residue
D	ASP42
D	VAL43
D	GOL1299
D	HOH2011
E	GOL1299
F	LYS28
F	ASP42

---

site_id	BC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL F1300

Chain	Residue
E	TRP50
E	PRO78
F	PHE213
F	ASN215
F	PHE254
F	ARG277
F	ALA279
F	ALA280

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	Binding site: {"evidences":[{"source":"PubMed","id":"14765200","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16370017","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16604208","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17985882","evidenceCode":"ECO:0000269"},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"OCT-2005","submissionDatabase":"PDB data bank","title":"Substrates and inhibitors of the fluorinase from Streptomyces cattleya.","authors":["Mcewan A.R.","Deng H.","Mcglinchey R.P.","Robinson D.R.","O'Hagan D.","Naismith J.H."]}},{"source":"Reference","evidenceCode":"ECO:0000269","citation":{"citationType":"submission","publicationDate":"FEB-2014","submissionDatabase":"PDB data bank","title":"Structure of a bacterial fluorinating enzyme with.","authors":["Thomson S.","Mcmahon S.A.","Naismith J.H.","O'Hagan D."]}}]}

Chain

Residue

Details

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