2C4U

Crystal structure of the apo form of the 5'-Fluoro-5'-deoxyadenosine synthase enzyme from Streptomyces cattleya

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity
A	0033846	molecular_function	adenosyl-fluoride synthase activity
B	0016740	molecular_function	transferase activity
B	0033846	molecular_function	adenosyl-fluoride synthase activity
C	0016740	molecular_function	transferase activity
C	0033846	molecular_function	adenosyl-fluoride synthase activity
D	0016740	molecular_function	transferase activity
D	0033846	molecular_function	adenosyl-fluoride synthase activity
E	0016740	molecular_function	transferase activity
E	0033846	molecular_function	adenosyl-fluoride synthase activity
F	0016740	molecular_function	transferase activity
F	0033846	molecular_function	adenosyl-fluoride synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A1299

Chain	Residue
A	TRP50
A	TYR77
A	PRO78
A	HOH2082
B	PHE254
B	ALA279
B	HOH2072

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A1300

Chain	Residue
A	ASP42
A	HOH2083
A	HOH2084
B	ASP42
B	VAL43
A	THR19
A	LYS28

---

site_id	AC3
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A1301

Chain	Residue
A	PHE213
A	ASN215
A	PHE254
A	ARG277
A	ALA279
A	HOH2085
C	TRP50
C	PRO78

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL B1299

Chain	Residue
B	THR19
B	LYS28
B	ASP42
B	HOH2086
B	HOH2087
B	HOH2088
C	ASP42
C	VAL43

---

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL C1299

Chain	Residue
A	ASP42
A	HOH2015
C	THR19
C	LYS28
C	ASP42
C	HOH2061

---

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL C1300

Chain	Residue
B	TRP50
B	TYR77
B	PRO78
C	PHE213
C	ASN215
C	PHE254
C	ALA279

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GOL D1299

Chain	Residue
D	LYS28
D	ASP42
E	ASP42
E	VAL43
F	GOL1299

---

site_id	AC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL D1300

Chain	Residue
D	ASP16
D	TYR77
D	THR80
D	PHE156
D	TYR157
D	SER158
E	PHE213

---

site_id	AC9
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL E1299

Chain	Residue
E	THR19
E	LYS28
E	ASP42
E	HOH2004
F	ASP42
F	GOL1299

---

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL F1299

Chain	Residue
D	ASP42
D	VAL43
D	GOL1299
D	HOH2011
E	GOL1299
F	LYS28
F	ASP42

---

site_id	BC2
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL F1300

Chain	Residue
E	TRP50
E	PRO78
F	PHE213
F	ASN215
F	PHE254
F	ARG277
F	ALA279
F	ALA280

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	48
Details	BINDING: BINDING => ECO:0000269|PubMed:14765200, ECO:0000269|PubMed:16370017, ECO:0000269|PubMed:16604208, ECO:0000269|PubMed:17985882, ECO:0000269|Ref.4, ECO:0000269|Ref.8

Chain	Residue	Details
A	ASP16
B	ASP21
B	TYR77
B	SER158
B	ASP210
B	ASN215
B	SER269
B	ARG277
C	ASP16
C	ASP21
C	TYR77
A	ASP21
C	SER158
C	ASP210
C	ASN215
C	SER269
C	ARG277
D	ASP16
D	ASP21
D	TYR77
D	SER158
D	ASP210
A	TYR77
D	ASN215
D	SER269
D	ARG277
E	ASP16
E	ASP21
E	TYR77
E	SER158
E	ASP210
E	ASN215
E	SER269
A	SER158
E	ARG277
F	ASP16
F	ASP21
F	TYR77
F	SER158
F	ASP210
F	ASN215
F	SER269
F	ARG277
A	ASP210
A	ASN215
A	SER269
A	ARG277
B	ASP16

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