2C4N

NagD from E.coli K-12 strain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0008253	molecular_function	5'-nucleotidase activity
A	0016787	molecular_function	hydrolase activity
A	0016791	molecular_function	phosphatase activity
A	0046050	biological_process	UMP catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A1251

Chain	Residue
A	ASP9
A	ASP11
A	ASP201
A	PO41253
A	HOH2093
A	HOH2097

---

site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE PO4 A1252

Chain	Residue
A	ASN202
A	THR205
A	PO41253
A	HOH2097
A	ASN43
A	ASP146
A	LYS176

---

site_id	AC3
Number of Residues	10
Details	BINDING SITE FOR RESIDUE PO4 A1253

Chain	Residue
A	ASP9
A	ASP11
A	LEU41
A	THR42
A	ASN43
A	TYR44
A	LYS176
A	MG1251
A	PO41252
A	HOH2111

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"16430214","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor/acceptor","evidences":[{"source":"PubMed","id":"16430214","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16430214","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C4N","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	Site: {"description":"Orients D-11 for proton transfer during catalytic turnover","evidences":[{"source":"PubMed","id":"16430214","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	Site: {"description":"Confers substrate specificity"}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1lvh

Chain	Residue	Details
A	THR143
A	LYS176

---