2C4E

Crystal Structure of Methanocaldococcus jannaschii Nucleoside Kinase - An Archaeal Member of the Ribokinase Family

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006796	biological_process	phosphate-containing compound metabolic process
A	0008906	molecular_function	inosine kinase activity
A	0009165	biological_process	nucleotide biosynthetic process
A	0009224	biological_process	CMP biosynthetic process
A	0016301	molecular_function	kinase activity
A	0016740	molecular_function	transferase activity
A	0019206	molecular_function	nucleoside kinase activity
A	0043771	molecular_function	cytidine kinase activity
A	0106366	molecular_function	guanosine kinase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG A 360

Chain	Residue
A	HOH2020
A	HOH2058
A	HOH2076
A	HOH2077
A	HOH2078
A	HOH2109

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Functional Information from PROSITE/UniProt

site_id	PS00583
Number of Residues	25
Details	PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGaAaNTAvgIkKLGvnsellscvG

Chain	Residue	Details
A	GLY42-GLY66

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site_id	PS00584
Number of Residues	14
Details	PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DPtGAGDsyrAGFL

Chain	Residue	Details
A	ASP241-LEU254

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"16929110","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	15
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16929110","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C49","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"16929110","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	4
Details	Annotated By Reference To The Literature 1rk2

Chain	Residue	Details
A	ALA245
A	GLY246
A	ASP247
A	GLY244

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