Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0004540 | molecular_function | RNA nuclease activity |
| A | 0004866 | molecular_function | endopeptidase inhibitor activity |
| A | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0004540 | molecular_function | RNA nuclease activity |
| B | 0004866 | molecular_function | endopeptidase inhibitor activity |
| B | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1159 |
| Chain | Residue |
| A | PRO64 |
| A | GLY65 |
| A | ARG69 |
| A | HOH2241 |
| A | HOH2242 |
| A | HOH2243 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1160 |
| Chain | Residue |
| A | LYS122 |
| A | LYS123 |
| A | HOH2244 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1161 |
| Chain | Residue |
| A | LYS27 |
| A | ARG83 |
| A | TYR103 |
| A | HOH2245 |
| A | HOH2246 |
| A | HOH2247 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1162 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1163 |
| Chain | Residue |
| A | THR70 |
| A | ARG72 |
| A | HOH2248 |
| A | HOH2249 |
| A | HOH2250 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1164 |
| Chain | Residue |
| A | VAL36 |
| A | ALA37 |
| A | SER38 |
| A | HOH2252 |
| A | HOH2253 |
| A | HOH2254 |
| A | HOH2255 |
| B | LYS66 |
| B | SER67 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1165 |
| Chain | Residue |
| A | ALA37 |
| A | PHE82 |
| A | ARG83 |
| A | HOH2247 |
| A | HOH2256 |
| A | HOH2257 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1155 |
| Chain | Residue |
| A | HIS18 |
| B | ARG126 |
| B | HOH2190 |
| B | HOH2215 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1165 |
| Chain | Residue |
| A | LYS39 |
| B | PRO64 |
| B | ARG69 |
| B | HOH2230 |
| B | HOH2231 |
| B | HOH2232 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1166 |
| Chain | Residue |
| B | LYS122 |
| B | LYS123 |
| B | HOH2186 |
| B | HOH2233 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1167 |
| Chain | Residue |
| B | LYS27 |
| B | ARG83 |
| B | TYR103 |
| B | HOH2234 |
| B | HOH2235 |
| B | HOH2236 |
| B | HOH2237 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1168 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1170 |
| Chain | Residue |
| B | ARG72 |
| B | HOH2240 |
| B | HOH2241 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1173 |
| Chain | Residue |
| A | SER128 |
| A | HOH2214 |
| B | ARG126 |
| B | SER128 |
| B | HOH2246 |
| site_id | BC6 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE 2PE A 1145 |
| Chain | Residue |
| A | CYS117 |
| A | PRO118 |
| A | LYS119 |
| A | ILE120 |
| A | CYS142 |
| A | SER144 |
| A | HOH2068 |
| A | HOH2081 |
| A | HOH2231 |
| B | LEU121 |
| B | ASN139 |
| B | PHE141 |
| B | CYS142 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE 2PE A 1146 |
| Chain | Residue |
| A | GLN31 |
| A | LYS123 |
| A | CYS124 |
| A | ASN139 |
| A | GLY140 |
| A | HOH2233 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO A 1153 |
| site_id | BC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO A 1155 |
| Chain | Residue |
| A | GLN15 |
| A | SER111 |
| A | SER111 |
| A | SER112 |
| A | HOH2237 |
| A | HOH2237 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1156 |
| Chain | Residue |
| A | ASN84 |
| A | SER85 |
| A | HOH2171 |
| site_id | CC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE 2PE B 1156 |
| Chain | Residue |
| A | CYS142 |
| A | GLY143 |
| B | MET114 |
| B | CYS117 |
| B | LYS119 |
| B | HOH2217 |
| B | HOH2218 |
| B | HOH2219 |
| B | HOH2220 |
| A | ALA32 |
| A | GLY137 |
| A | PHE141 |
| site_id | CC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE 2PE B 1157 |
| Chain | Residue |
| B | TYR17 |
| B | ILE120 |
| B | LYS122 |
| B | LEU131 |
| B | EDO1159 |
| B | HOH2198 |
| B | HOH2222 |
| B | HOH2223 |
| site_id | CC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1159 |
| Chain | Residue |
| B | TYR13 |
| B | LYS19 |
| B | 2PE1157 |
| site_id | CC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO B 1160 |
| Chain | Residue |
| B | LYS98 |
| B | THR99 |
| B | THR100 |
| B | ASP101 |
| B | THR105 |
| B | THR107 |
| B | EDO1164 |
| site_id | CC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1161 |
| Chain | Residue |
| B | ARG72 |
| B | SER92 |
| B | HOH2127 |
| B | HOH2227 |
| site_id | CC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EDO B 1162 |
| Chain | Residue |
| B | PHE82 |
| B | ARG83 |
| B | ASN84 |
| B | HOH2142 |
| B | HOH2144 |
| B | HOH2228 |
| site_id | CC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1163 |
| Chain | Residue |
| B | ASP12 |
| B | GLN15 |
| B | THR16 |
| B | HOH2034 |
| B | HOH2229 |
| site_id | CC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO B 1164 |
| Chain | Residue |
| B | LYS98 |
| B | LYS98 |
| B | THR107 |
| B | EDO1160 |
| site_id | DC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT A 1157 |
| Chain | Residue |
| A | HOH2016 |
| A | HOH2018 |
| A | HOH2238 |
| A | HOH2239 |
| site_id | DC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE FMT A 1158 |
| Chain | Residue |
| A | ARG72 |
| A | HOH2240 |
| site_id | DC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT B 1174 |
| Chain | Residue |
| B | HOH2159 |
| B | HOH2171 |
| B | HOH2248 |
| B | HOH2249 |
| site_id | DC4 |
| Number of Residues | 10 |
| Details | Binding site for residues GOL A1148 and EDO A1154 |
| Chain | Residue |
| A | LYS98 |
| A | LYS98 |
| A | THR99 |
| A | THR100 |
| A | ASP101 |
| A | THR105 |
| A | THR107 |
| A | THR107 |
| A | HOH2234 |
| A | HOH2234 |
| site_id | DC5 |
| Number of Residues | 13 |
| Details | Binding site for residues MES B1158 and SO4 B1169 |
| Chain | Residue |
| B | TRP35 |
| B | ALA37 |
| B | GLY40 |
| B | PHE82 |
| B | ARG83 |
| B | ASN84 |
| B | SER85 |
| B | ARG87 |
| B | ALA102 |
| B | HOH2224 |
| B | HOH2225 |
| B | HOH2226 |
| B | HOH2238 |
| site_id | DC6 |
| Number of Residues | 13 |
| Details | Binding site for residues MES B1158 and SO4 B1169 |
| Chain | Residue |
| B | TRP35 |
| B | ALA37 |
| B | GLY40 |
| B | PHE82 |
| B | ARG83 |
| B | ASN84 |
| B | SER85 |
| B | ARG87 |
| B | ALA102 |
| B | HOH2224 |
| B | HOH2225 |
| B | HOH2226 |
| B | HOH2238 |
| site_id | DC7 |
| Number of Residues | 13 |
| Details | Binding site for residues MES B1158 and SO4 B1169 |
| Chain | Residue |
| B | TRP35 |
| B | ALA37 |
| B | GLY40 |
| B | PHE82 |
| B | ARG83 |
| B | ASN84 |
| B | SER85 |
| B | ARG87 |
| B | ALA102 |
| B | HOH2224 |
| B | HOH2225 |
| B | HOH2226 |
| B | HOH2238 |
| site_id | DC8 |
| Number of Residues | 13 |
| Details | Binding site for residues SO4 B1171 and SO4 B1172 |
| Chain | Residue |
| A | GLY137 |
| A | PRO138 |
| A | ASN139 |
| A | GLY140 |
| B | LYS66 |
| B | SER67 |
| B | GLY68 |
| B | SER92 |
| B | MET114 |
| B | HOH2242 |
| B | HOH2243 |
| B | HOH2244 |
| B | HOH2245 |
Functional Information from PROSITE/UniProt
| site_id | PS00286 |
| Number of Residues | 20 |
| Details | SQUASH_INHIBITOR Squash family of serine protease inhibitors signature. CPkilkkCrrDsDClagCvC |
| Chain | Residue | Details |
| A | CYS117-CYS136 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Reactive bond"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | Cross-link: {"description":"Isoaspartyl glycine isopeptide (Asp-Gly); alternate","evidences":[{"source":"PubMed","id":"10801322","evidenceCode":"ECO:0000269"}]} |
