Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005829 | cellular_component | cytosol |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0008906 | molecular_function | inosine kinase activity |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0009224 | biological_process | CMP biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0019206 | molecular_function | nucleoside kinase activity |
| A | 0043771 | molecular_function | cytidine kinase activity |
| A | 0106366 | molecular_function | guanosine kinase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0008906 | molecular_function | inosine kinase activity |
| B | 0009165 | biological_process | nucleotide biosynthetic process |
| B | 0009224 | biological_process | CMP biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016740 | molecular_function | transferase activity |
| B | 0019206 | molecular_function | nucleoside kinase activity |
| B | 0043771 | molecular_function | cytidine kinase activity |
| B | 0106366 | molecular_function | guanosine kinase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A1302 |
| Chain | Residue |
| A | HOH2046 |
| A | HOH2056 |
| A | HOH2057 |
| A | HOH2066 |
| A | HOH2077 |
| A | HOH2079 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG A1303 |
| Chain | Residue |
| A | HOH2042 |
| A | HOH2054 |
| A | HOH2018 |
| A | HOH2019 |
| A | HOH2021 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B1302 |
| Chain | Residue |
| B | HOH2014 |
| B | HOH2040 |
| B | HOH2041 |
| B | HOH2053 |
| B | HOH2081 |
| B | HOH2082 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE MG B1303 |
| Chain | Residue |
| B | HOH2036 |
| B | HOH2048 |
| B | HOH2058 |
| B | HOH2059 |
| B | HOH2078 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ADN A1301 |
| Chain | Residue |
| A | HIS13 |
| A | ALA15 |
| A | ASP17 |
| A | GLY42 |
| A | GLY43 |
| A | ASN47 |
| A | THR111 |
| A | PHE113 |
| A | GLN163 |
| A | ASP164 |
| A | ASP247 |
| A | CYS283 |
| A | HOH2077 |
| A | HOH2078 |
| B | SER31 |
| B | GLN33 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE ANP A1304 |
| Chain | Residue |
| A | GLN109 |
| A | ASN186 |
| A | THR214 |
| A | GLY216 |
| A | GLY219 |
| A | CYS233 |
| A | ILE234 |
| A | VAL239 |
| A | THR243 |
| A | ALA245 |
| A | GLY246 |
| A | ALA274 |
| A | HOH2062 |
| A | HOH2072 |
| A | HOH2079 |
| A | HOH2080 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ADN B1301 |
| Chain | Residue |
| B | HIS13 |
| B | ALA15 |
| B | ASP17 |
| B | GLY42 |
| B | GLY43 |
| B | ALA44 |
| B | HOH2080 |
| site_id | AC8 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE ANP B1304 |
| Chain | Residue |
| B | ASN186 |
| B | THR214 |
| B | LYS215 |
| B | GLY216 |
| B | GLY219 |
| B | CYS233 |
| B | ILE234 |
| B | VAL239 |
| B | PRO242 |
| B | THR243 |
| B | GLY244 |
| B | ALA245 |
| B | GLY246 |
| B | TYR249 |
| B | ARG250 |
| B | ALA274 |
| B | HOH2060 |
| B | HOH2081 |
| B | HOH2082 |
Functional Information from PROSITE/UniProt
| site_id | PS00583 |
| Number of Residues | 25 |
| Details | PFKB_KINASES_1 pfkB family of carbohydrate kinases signature 1. GGaAaNTAvgIkKLGvnsellscvG |
| Chain | Residue | Details |
| A | GLY42-GLY66 | |
| site_id | PS00584 |
| Number of Residues | 14 |
| Details | PFKB_KINASES_2 pfkB family of carbohydrate kinases signature 2. DPtGAGDsyrAGFL |
| Chain | Residue | Details |
| A | ASP241-LEU254 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PubMed","id":"16929110","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 30 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16929110","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2C49","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"source":"PubMed","id":"16929110","evidenceCode":"ECO:0000305"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rk2 |
| Chain | Residue | Details |
| A | ALA245 | |
| A | GLY246 | |
| A | ASP247 | |
| A | GLY244 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1rk2 |
| Chain | Residue | Details |
| B | ALA245 | |
| B | GLY246 | |
| B | ASP247 | |
| B | GLY244 | |
