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2C2Y

Three Dimensional Structure of bifunctional methylenetetrahydrofolate dehydrogenase-cyclohydrolase from Mycobacterium tuberculosis

Functional Information from GO Data
ChainGOidnamespacecontents
A0000105biological_processL-histidine biosynthetic process
A0003824molecular_functioncatalytic activity
A0004477molecular_functionmethenyltetrahydrofolate cyclohydrolase activity
A0004488molecular_functionmethylenetetrahydrofolate dehydrogenase (NADP+) activity
A0005576cellular_componentextracellular region
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006164biological_processpurine nucleotide biosynthetic process
A0006730biological_processone-carbon metabolic process
A0008652biological_processamino acid biosynthetic process
A0009086biological_processmethionine biosynthetic process
A0016491molecular_functionoxidoreductase activity
A0016787molecular_functionhydrolase activity
A0035999biological_processtetrahydrofolate interconversion
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01576
ChainResidueDetails
AGLY165
ATHR192
AVAL233

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1a4i
ChainResidueDetails
ALYS53

237735

PDB entries from 2025-06-18

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