2C2I
Structure and function of Rv0130, a conserved hypothetical protein from M.tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
| A | 0080023 | molecular_function | (2E)-enoyl-CoA hydratase activity |
| B | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
| B | 0080023 | molecular_function | (2E)-enoyl-CoA hydratase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 10 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"description":"in homodimeric partner","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Site: {"description":"Important for catalytic activity","evidences":[{"evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Transition state stabilizer","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| A | ASP40 | |
| A | ILE60 | |
| A | HIS45 | |
| A | GLY63 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| B | ASP40 | |
| B | ILE60 | |
| B | HIS45 | |
| B | GLY63 |
