2C2I
Structure and function of Rv0130, a conserved hypothetical protein from M.tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
| B | 0004300 | molecular_function | enoyl-CoA hydratase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0018812 | molecular_function | 3-hydroxyacyl-CoA dehydratase activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE60 | |
| A | PRO97 | |
| B | ILE60 | |
| B | PRO97 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | BINDING: in homodimeric partner => ECO:0000305 |
| Chain | Residue | Details |
| A | ALA86 | |
| A | GLN124 | |
| A | ARG148 | |
| B | ALA86 | |
| B | GLN124 | |
| B | ARG148 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | SITE: Important for catalytic activity => ECO:0000305 |
| Chain | Residue | Details |
| A | ASP40 | |
| A | HIS45 | |
| B | ASP40 | |
| B | HIS45 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | SITE: Transition state stabilizer => ECO:0000255 |
| Chain | Residue | Details |
| A | GLN42 | |
| B | GLN42 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| A | ASP40 | |
| A | ILE60 | |
| A | HIS45 | |
| A | GLY63 |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1s9c |
| Chain | Residue | Details |
| B | ASP40 | |
| B | ILE60 | |
| B | HIS45 | |
| B | GLY63 |
