2C00
Crystal Structure of Biotin Carboxylase from Pseudomonas aeruginosa in apo form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0003989 | molecular_function | acetyl-CoA carboxylase activity |
| A | 0004075 | molecular_function | biotin carboxylase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0006631 | biological_process | fatty acid metabolic process |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016874 | molecular_function | ligase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 2001295 | biological_process | malonyl-CoA biosynthetic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0003989 | molecular_function | acetyl-CoA carboxylase activity |
| B | 0004075 | molecular_function | biotin carboxylase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006629 | biological_process | lipid metabolic process |
| B | 0006631 | biological_process | fatty acid metabolic process |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016874 | molecular_function | ligase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 2001295 | biological_process | malonyl-CoA biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 A1446 |
| Chain | Residue |
| A | LYS238 |
| A | ARG292 |
| A | GLN294 |
| A | VAL295 |
| A | GLU296 |
| A | ARG338 |
| A | HOH2185 |
| A | HOH2310 |
| A | HOH2311 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B1446 |
| Chain | Residue |
| B | LYS238 |
| B | ARG292 |
| B | GLN294 |
| B | VAL295 |
| B | GLU296 |
| B | ARG338 |
| B | HOH2177 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P24182 |
| Chain | Residue | Details |
| A | ARG292 | |
| B | ARG292 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P24182 |
| Chain | Residue | Details |
| A | LYS116 | |
| A | ARG338 | |
| B | LYS116 | |
| B | LYS159 | |
| B | GLY165 | |
| B | GLU201 | |
| B | HIS209 | |
| B | HIS236 | |
| B | LYS238 | |
| B | ARG292 | |
| B | VAL295 | |
| A | LYS159 | |
| B | ARG338 | |
| A | GLY165 | |
| A | GLU201 | |
| A | HIS209 | |
| A | HIS236 | |
| A | LYS238 | |
| A | ARG292 | |
| A | VAL295 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00409 |
| Chain | Residue | Details |
| A | GLU276 | |
| A | GLU288 | |
| A | ASN290 | |
| B | GLU276 | |
| B | GLU288 | |
| B | ASN290 |
