2BUE
Structure of AAC(6')-Ib in complex with Ribostamycin and Coenzyme A.
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0016410 | molecular_function | N-acyltransferase activity |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0016747 | molecular_function | acyltransferase activity, transferring groups other than amino-acyl groups |
| A | 0016779 | molecular_function | nucleotidyltransferase activity |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047663 | molecular_function | aminoglycoside 6'-N-acetyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 24 |
| Details | BINDING SITE FOR RESIDUE COA A1200 |
| Chain | Residue |
| A | HIS44 |
| A | LEU128 |
| A | GLY129 |
| A | THR130 |
| A | ASN157 |
| A | LEU158 |
| A | ARG159 |
| A | ARG162 |
| A | LYS166 |
| A | RIO1201 |
| A | HOH2191 |
| A | TRP48 |
| A | HOH2196 |
| A | HOH2239 |
| A | HOH2240 |
| A | HOH2242 |
| A | HOH2243 |
| A | GLN116 |
| A | LEU117 |
| A | LEU118 |
| A | LEU124 |
| A | GLY125 |
| A | LYS126 |
| A | GLY127 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE RIO A1201 |
| Chain | Residue |
| A | TRP48 |
| A | GLY50 |
| A | TYR65 |
| A | GLU73 |
| A | GLN91 |
| A | TYR93 |
| A | TRP102 |
| A | TRP103 |
| A | ASP115 |
| A | ASP152 |
| A | COA1200 |
| A | HOH2186 |
| A | HOH2196 |
| A | HOH2219 |
| A | HOH2224 |
| A | HOH2244 |
| A | HOH2245 |
| A | HOH2246 |
| A | HOH2247 |
| A | HOH2248 |
| A | HOH2249 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A1202 |
| Chain | Residue |
| A | GLU145 |
| A | ASP179 |
| A | HOH2172 |
| A | HOH2177 |
| A | HOH2182 |
| A | HOH2220 |
| A | HOH2225 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA A1203 |
| Chain | Residue |
| A | GLU38 |
| A | ARG194 |
| A | SER197 |
| A | ALA199 |
| A | HOH2039 |
| A | HOH2236 |
