2BUE

Structure of AAC(6')-Ib in complex with Ribostamycin and Coenzyme A.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016410	molecular_function	N-acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0046677	biological_process	response to antibiotic
A	0047663	molecular_function	aminoglycoside 6'-N-acetyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	BINDING SITE FOR RESIDUE COA A1200

Chain	Residue
A	HIS44
A	LEU128
A	GLY129
A	THR130
A	ASN157
A	LEU158
A	ARG159
A	ARG162
A	LYS166
A	RIO1201
A	HOH2191
A	TRP48
A	HOH2196
A	HOH2239
A	HOH2240
A	HOH2242
A	HOH2243
A	GLN116
A	LEU117
A	LEU118
A	LEU124
A	GLY125
A	LYS126
A	GLY127

---

site_id	AC2
Number of Residues	21
Details	BINDING SITE FOR RESIDUE RIO A1201

Chain	Residue
A	TRP48
A	GLY50
A	TYR65
A	GLU73
A	GLN91
A	TYR93
A	TRP102
A	TRP103
A	ASP115
A	ASP152
A	COA1200
A	HOH2186
A	HOH2196
A	HOH2219
A	HOH2224
A	HOH2244
A	HOH2245
A	HOH2246
A	HOH2247
A	HOH2248
A	HOH2249

---

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA A1202

Chain	Residue
A	GLU145
A	ASP179
A	HOH2172
A	HOH2177
A	HOH2182
A	HOH2220
A	HOH2225

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CA A1203

Chain	Residue
A	GLU38
A	ARG194
A	SER197
A	ALA199
A	HOH2039
A	HOH2236

---